Abstract
We proposed an approach to new compounds based on conjugates of 5-methyl-2-phenylpyrazol-3-ones and 1-aminoadamantanes containing fragments of the neuroactive drugs Edaravone, Amantadine, and Memantine.
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Dedicated to the Academician of the Russian Academy of Sciences V. A. Tartakovsky on the occasion of his 90th birthday.
his work was financially supported by the Russian Science Foundation (Project No. 19-13-00378-n). The work was performed using the equipment of the Center for Collective Use of the Institute of Physiologically Active Substances of the Russian Academy of Sciences, funded within the framework of the Russian state assignment (Theme No. 0090-2019-0005).
No human or animal subjects were used in this research.
The authors declare no competing interests.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1794–1800, August, 2022.
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Aksinenko, A.Y., Goreva, T.V., Epishina, T.A. et al. Synthesis of conjugates of 5-methyl-2-phenylpyrazol-3-ones and 1-aminoadamantanes as potential neuroprotective agents. Russ Chem Bull 71, 1794–1800 (2022). https://doi.org/10.1007/s11172-022-3591-2
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DOI: https://doi.org/10.1007/s11172-022-3591-2