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Sorption of pyridine-3-carboxylic acid by the Dowex-50 sulfonic cation-exchange resin in the NiII and CuII forms

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Abstract

The equilibrium distribution of components between aqueous solutions containing pyridine-3-carboxylic acid and Dowex-50 sulfonic cation-exchange resin in the NiII or CuII form was studied. The counterionic composition of the sulfonic cation-exchange resin was determined by solving a system of equations for the selectivity coefficients of the binary ion exchanges and the material balance equation. The experimental and calculated results for the sorption processes and the data of FT-IR spectroscopy and 13C CPMAS NMR spectroscopy of solid samples showed that pyridine-3-carboxylic acid in the Dowex-50 sulfonic cation-exchange resin is presented by the protonated [H2L]+ form or [CuHL]2+ cations. High distribution coefficients suggest that pyridine-3-carboxylic acid and metal cations (CuII, NiII) can be concentrated in the Dowex-50 sulfonic cation-exchange resin. The Dowex-50 sulfonic cation-exchange resin appears to be useful as a container for drugs based on pyridine-3-carboxylic acid and divalent transition metal cations, such as CuII and NiII.

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Authors and Affiliations

  1. Federal Research Center of Coal and Coal Chemistry, Siberian Branch of Russian Academy of Sciences, 18 Sovetskii prosp., 650000, Kemerovo, Russian Federation

    H. N. Altshuler, N. V. Malyshenko, V. N. Nekrasov & O. H. Altshuler

  2. Kemerovo State University, 6 ul. Krasnaya, 650000, Kemerovo, Russian Federation

    O. H. Altshuler

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  1. H. N. Altshuler
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  2. N. V. Malyshenko
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  3. V. N. Nekrasov
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  4. O. H. Altshuler
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Correspondence to H. N. Altshuler.

Additional information

This work was carried out in terms of state assignment of the Federal Research Center of Coal and Coal Chemistry (Siberian Branch of Russian Academy of Sciences) (Project No 121031500194-5) using equipment of the Center for Collective Use of the Federal Research Center of Coal and Coal Chemistry (Siberian Branch of Russian Academy of Sciences).

This paper does not contain descriptions of studies on animals or humans.

The authors declare no competing interests.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1421–1428, August, 2021.

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Altshuler, H.N., Malyshenko, N.V., Nekrasov, V.N. et al. Sorption of pyridine-3-carboxylic acid by the Dowex-50 sulfonic cation-exchange resin in the NiII and CuII forms. Russ Chem Bull 70, 1421–1428 (2021). https://doi.org/10.1007/s11172-021-3235-y

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  • DOI: https://doi.org/10.1007/s11172-021-3235-y

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