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Synthesis of enaminones containing diverse N,N-disubstitution via simple transamination: a study with sustainable catalyst-free operation

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Abstract

A systematic investigation on the synthesis of β-enaminones containing diverse N,N-disubstitution via the transamination of N,N-dimethyl amino functionalized β-enaminones and secondary amines has been conducted by employing biomass available green solvent ethyl lactate as reaction medium. A class of β-enaminones containing different N,N-disubstitutions have been smoothly synthesized under the sustainable conditions without using any catalyst.

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Acknowledgements

This work is financially supported by Natural Science Foundation of China (21562025) and Natural Science Foundation of Jiangxi Province (20161ACB21010).

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Authors and Affiliations

  1. College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, 330022, People’s Republic of China

    Yong Gao, Yunyun Liu, Li Wei & Jieping Wan

Authors
  1. Yong Gao
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  2. Yunyun Liu
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  3. Li Wei
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  4. Jieping Wan
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Correspondence to Jieping Wan.

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Gao, Y., Liu, Y., Wei, L. et al. Synthesis of enaminones containing diverse N,N-disubstitution via simple transamination: a study with sustainable catalyst-free operation. Res Chem Intermed 43, 5547–5555 (2017). https://doi.org/10.1007/s11164-017-2946-z

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  • DOI: https://doi.org/10.1007/s11164-017-2946-z

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