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Synthesis of Ugi-4CR boronate analogues via microwave irradiation

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Abstract

The synthetic condition for the synthesis of boronate ester Ugi-4CR analogs under mild conditions was developed. The reported reactions were carried out in methanol and promoted by microwave heating. This synthetic strategy could provide unique access to a broad range of boron-containing chemical libraries.

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Acknowledgments

This research was supported by the Ministry of Science and Technology in Taiwan (MST-103-2113-M-032-010). We thank the Department of Chemistry of Tamkang University for the equipment and financial support. We thank Ms. Shen–Shen Chen for conducting the 11B NMR experiments.

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Authors and Affiliations

  1. Department of Chemistry, Tamkang University, No. 151 Yingzhuan Rd., Tamsui District, New Taipei City, 25137, Taiwan, ROC

    Chao-Yu Hsiao, Shi-Qing Huang, Wan-Hsing Lien, Chen-Yun Hsu, Kun-lin Hsieh, Meng-Hsuan Lin, Meng-Ju Wu, Chia-Chieh Fu, Hsien-Chi Chen, Hao-Ping Fang, Chia-Jung Li & Po-Shen Pan

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  1. Chao-Yu Hsiao
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  2. Shi-Qing Huang
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  3. Wan-Hsing Lien
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  4. Chen-Yun Hsu
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  5. Kun-lin Hsieh
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  6. Meng-Hsuan Lin
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  9. Hsien-Chi Chen
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  11. Chia-Jung Li
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  12. Po-Shen Pan
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Correspondence to Po-Shen Pan.

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Hsiao, CY., Huang, SQ., Lien, WH. et al. Synthesis of Ugi-4CR boronate analogues via microwave irradiation. Res Chem Intermed 43, 3585–3597 (2017). https://doi.org/10.1007/s11164-016-2433-y

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  • DOI: https://doi.org/10.1007/s11164-016-2433-y

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