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1,3-Disulfonic acid benzimidazolium chloride as an efficient and recyclable ionic liquid catalyst for the synthesis of 3,4-dihydropyrimidine-2-(1H)-ones/thiones

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Abstract

1,3-Disulfonic acid benzimidazolium chloride ionic liquid ([Dsbim]Cl) was prepared, characterized and applied as an efficient, homogeneous and recyclable catalyst for the synthesis of 3,4-dihydropyrimidine-2-(1H)-ones/thiones through the one-pot three-component condensation of aromatic aldehydes, urea/thiourea and ethyl acetoacetate under solvent-free conditions. The key advantages of this novel protocol are its short reaction time, high yields, mild and clean conditions, practical simplicity and its capacity for reuse several times without a noticeable decrease in catalytic activity.

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Acknowledgments

I gratefully acknowledge the Islamic Azad University of Lamerd Research Councils for support of this work.

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Authors and Affiliations

  1. Department of Chemistry, Lamerd Branch, Islamic Azad University, Lamerd, Fars, Iran

    Mohsen Abbasi

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  1. Mohsen Abbasi
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Correspondence to Mohsen Abbasi.

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Abbasi, M. 1,3-Disulfonic acid benzimidazolium chloride as an efficient and recyclable ionic liquid catalyst for the synthesis of 3,4-dihydropyrimidine-2-(1H)-ones/thiones. Res Chem Intermed 42, 3303–3314 (2016). https://doi.org/10.1007/s11164-015-2211-2

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