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Silica-bonded N-propylpiperazine sodium n-propionate as an efficient recyclable catalyst for one-pot synthesis of 2-amino-4-aryl-4H,8H-6-methyl-8-oxo-pyrano[3,2-b]pyran derivatives

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Abstract

An efficient and convenient method for synthesis of a series of 2-amino-4-aryl-4H,8H-6-methyl-8-oxo-pyrano[3,2-b]pyran derivatives by one-pot, three-component reaction of an aromatic aldehyde, malononitrile or a cyanoacetate, and 5-hydroxy-2-methyl-4H-pyran-4-one (allomaltol) in the presence of a catalytic amount of silica-bonded N-propylpiperazine sodium n-propionate (SBPPSP), in aqueous ethanol, is described. The method has the advantages of short reaction time, mild reaction conditions, high yields, and convenience.

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Acknowledgments

The author Mansoor would like to express his gratitude to the management of C. Abdul Hakeem College, Melvisharam 632 509, Tamil Nadu, India, for the use of their facilities and their general support.

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Authors and Affiliations

  1. Research Department of Chemistry, Bioactive Organic Molecule Synthetic Unit, C. Abdul Hakeem College, Melvisharam, 632 509, Tamil Nadu, India

    Syed Sheik Mansoor & S. P. N. Sudhan

  2. Department of Chemistry, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia

    Azhar Ariffin

Authors
  1. Syed Sheik Mansoor
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  2. Azhar Ariffin
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  3. S. P. N. Sudhan
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Correspondence to Syed Sheik Mansoor.

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Mansoor, S.S., Ariffin, A. & Sudhan, S.P.N. Silica-bonded N-propylpiperazine sodium n-propionate as an efficient recyclable catalyst for one-pot synthesis of 2-amino-4-aryl-4H,8H-6-methyl-8-oxo-pyrano[3,2-b]pyran derivatives. Res Chem Intermed 41, 6687–6705 (2015). https://doi.org/10.1007/s11164-014-1769-4

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