Five series of samples of the substance containing total flavonoids were obtained from the aerial part of Scutellaria comosa Juz. The characteristics of an adaptogenic preparation being developed were determined by physicochemical studies: yellow crystalline powder, practically insoluble in water and CHCl3, poorly and slowly soluble in MeOH and EtOH (96%), mass loss on drying 5%, sulfate ash content 0.5%, heavy metal content 0.001%. Quantitative spectrophotometric determination of total flavonoids as norwogonin (5,7,8-trihydroxyflavone) revealed that the preparation contained at least 57.18% total flavonoids. Total flavonoids from S. comosa were shown to be a reliable effective tool for increasing the adaptive capabilities of the body, relieving physical fatigue and activating the recovery process.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 56, No. 10, pp. 34 – 38, October, 2022.
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Ergasheva, S.A., Mamatkhanova, M.A., Egamova, F.R. et al. Adaptogenic Activity of Flavonoids Isolated from the Aerial Part of Scutellaria comosa. Pharm Chem J 56, 1348–1352 (2023). https://doi.org/10.1007/s11094-023-02796-2
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DOI: https://doi.org/10.1007/s11094-023-02796-2