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Selective Extraction-Photometric Determination of Non-Steroidal Anti-Inflammatory Drugs

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Pharmaceutical Chemistry Journal Aims and scope

The possibility of extracting ion associates (IAs) of some non-steroidal anti-inflammatory drugs with the polymethine dye Astrafloxin was studied. The influence of medium pH, electrolyte concentration, nature of the extractant, and other factors on the IA extraction efficiency was established. Their selective determination in combined preparations was shown to be achievable by regulating the extraction conditions. The main chemical analytical and metrological characteristics of the developed methods were calculated.

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Authors and Affiliations

  1. Lesya Ukrainka Volyn National University, Lutsk, 43025, Ukraine

    I. Antal, Zh. Kormosh, I. Kotsan, T. Savchuk, S. Korolchuk, O. Yurchenko, S. Golub & S. Suprunovich

  2. Institute of Experimental Physics, Slovak Academy of Sciences, Kosice, Slovakia

    I. Antal

  3. Volyn Medical Institute, Lutsk, 43016, Ukraine

    N. Kormosh

  4. Lviv Polytechnic National University, Lviv, 79000, Ukraine

    Yu. Panchenko

  5. Chernivtsi National University, Chernivtsi, 58012, Ukraine

    V. Tkach

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  1. I. Antal
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Correspondence to Zh. Kormosh.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 55, No. 5, pp. 57 – 64, May, 2021.

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Antal, I., Kormosh, Z., Kotsan, I. et al. Selective Extraction-Photometric Determination of Non-Steroidal Anti-Inflammatory Drugs. Pharm Chem J 55, 516–523 (2021). https://doi.org/10.1007/s11094-021-02450-9

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