A series of β-p-toluylacrylate salts with various amines that retained the molecular fragment responsible for the antibacterial activity were synthesized. A new efficient method for obtaining β-aroylvinyl-1-pyridinium and -triphenylphosphonium bromides was proposed. Antibacterial testing showed that all investigated compounds possessed antibacterial properties.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 51, No. 10, pp. 22 – 25, October, 2017.
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Khachikyan, R.D., Ovakimyan, Z.G., Mikaelyan, A.A. et al. Synthesis and Biological Activity of β-Aroylacrylate Salts. Pharm Chem J 51, 873–876 (2018). https://doi.org/10.1007/s11094-018-1707-7
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DOI: https://doi.org/10.1007/s11094-018-1707-7