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Chemical Composition and Biological Activity of the BuOH Fraction from Chaga Melanin

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Pharmaceutical Chemistry Journal Aims and scope

The biologically active melanin fraction was isolated from the mushroom chaga and investigated. Terpenic and phenolic compounds were found in it by using mass spectrometry. The total contents of lipids, phenols, and carbohydrates were determined. It was found that the isolated fraction possessed antioxidant, fungicidal, fungistatic, and prebiotic activity for several microorganism groups.

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References

  1. M. D. Mashkovskii, Drugs [in Russian], Novaya Volna, Moscow (2005).

    Google Scholar 

  2. USSR State Pharmacopoeia: General analytical methods. Drug raw material [in Russian], No. 2, Meditsina, Moscow (1990).

  3. M. A. Sysoeva, O. Yu. Kuznetsova, V. S. Gamayurova, et al., Khim. Rastit. Syr'ya, No. 1, 41 – 47 (2005).

  4. A. N. Shivrina, Chaga and Its Therapeutic Application to Stage IV Cancer [in Russian], Medgiz, Leningrad (1959).

    Google Scholar 

  5. USSR State Pharmacopoeia, General analytical methods, No. 1, Meditsina, Moscow (1987).

  6. M. A. Sysoeva, O. Yu. Kuznetsova, V. S. Gamayurova, et al., Khim. Rastit. Syr’ya, No. 1, 41 – 47 (2005).

  7. S. E. Severin and G. A. Solov'eva, Practicum on Biochemistry [in Russian], Moscow (1989).

  8. R. Pohloudek-Fabini and T. Beyrich, Organic Analysis with Special Regard to Drugs, Akad. Verlagsges., Leipzig (1975), 608 pp

  9. I. Ya. Zakharova and L. V. Kosenko, Methods for Studying Microbial Polysaccharides [in Russian], Naukova Dumka, Kiev (1982).

  10. NIST (ChemistryWeb Book), http://webbook.nist.gov/chemistry/

  11. Handbook for Preclinical Drug Trials [in Russian], Part 1, Grif i K, Moscow (2012).

  12. A. I. Netrusov, Practicum on Microbiology [in Russian], Akademiya, Moscow (2005).

    Google Scholar 

  13. G. N. Pershin, Methods of Experimental Chemotherapy [in Russian], Meditsina, Moscow (1971).

    Google Scholar 

  14. Methods for Microbiological Control of Products for Children, Health Food, and Their Components [in Russian], Informatsionno-izdatel'skii Tsentr Minzdrava Rossii [Information Press Center of the Russian Ministry of Health], Moscow (1998).

  15. N. F. Izmerov, Acute Toxicity Parameters of Industrial Poisons (Handbook) [in Russian], Meditsina, Moscow (1977).

    Google Scholar 

  16. GOST R 52349 – 2005, Foodstuffs. Functional Foods. Terms and Definitions.

  17. N. A. Tyukavkina, Vopr. Pitan., No. 2, 33 – 37 (1996).

  18. G. K. Ziyatdinova, G. K. Budnikov, A. I. Samigullin, et al., Zh. Anal. Khim., 65(12), 1302 – 1308 (2010).

    Google Scholar 

  19. H. O. Conn and M. H. Floch, Am. J. Clin. Nutr., 23(12), 1588 – 1594 (1970); www.webbook.nist.gov/chemistry

  20. E. M. Gorskaya, V. M. Bondarenko, et al., RU Pat. 2,062,787, Jun. 27, 1996.

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Correspondence to M. A. Burmasova.

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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 51, No. 4, pp. 45 – 47, April, 2017.

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Burmasova, M.A., Sysoeva, M.A. Chemical Composition and Biological Activity of the BuOH Fraction from Chaga Melanin. Pharm Chem J 51, 292–294 (2017). https://doi.org/10.1007/s11094-017-1601-8

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  • DOI: https://doi.org/10.1007/s11094-017-1601-8

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