Skip to main content
SpringerLink
Log in

Antioxidant Activity of Medicinal Plants from Southeastern Kazakhstan

  • MEDICINAL PLANTS
  • Published:
Pharmaceutical Chemistry Journal Aims and scope

The antioxidant activity and total contents of phenolic compounds and flavonoids in extracts of several medicinal plants from southeastern Kazakhstan are studied. Antioxidant activity was evaluated in vitro using the cation-radical 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonate) (ABTS•+), the radical 2,2-diphenyl-1-picrylhydrazyl (DPPH•), and the FRAP method. The antioxidant and antiradical activities of the studied plants varied over wide ranges. Extracts of roots and the aerial part of Geranium collinum had the greatest antioxidant and antiradical activity; of Agrimonia asiatica, Alchemilla vulgaris, and Alhagi pseudalhagi, high activity. The antioxidant activities of H2O–EtOH and H2O–Me2CO extracts of G. collinum and A. asiatica showed a reliable correlation with their contents of phenolic compounds.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. E. B. Men’shikova, N. K. Zenkov, V. Z. Lankin, et al., Oxidative Stress [in Russian], ARTA, Novosibirsk (2008).

  2. J. A. Knight, Ann. Clin. Lab. Sci., 25(2), 111 – 121 (1995).

    CAS  PubMed  Google Scholar 

  3. T. Finkel, Curr. Opin. Cell Biol., 15(2), 247 – 541 (2003).

    Article  CAS  PubMed  Google Scholar 

  4. B. Halliwell, J. Gutteridge, and C. Cross, J. Lab. Clin. Med., 119, 598 – 622 (1992).

  5. E. N. Frankel and J. W. Finley, J. Agric. Food Chem., 56, 4901 – 4908 (2008).

  6. I. C. W. Arts and P. C. H. Hollman, Am. J. Clin. Nutr., 81(3), 317 – 325 (2005).

    Google Scholar 

  7. O. M. Andersen and K. R. Markham (eds.), in: Flavonoids: Chemistry, Biochemistry and Applications, CRC, Taylor & Francis Group, Boca Raton, FL (2005).

  8. E. Middleton, C. Kandaswami, and T. C. Theoharides, Pharmacol. Rev., 52(4), 15 – 25 (2000).

    Google Scholar 

  9. D. Huang, B. Ou, and R. L. Prior, J. Agric. Food Chem., 53, 1841 – 1856 (2005).

  10. J. K. Moon and T. Shibamoto, J. Agric. Food. Chem., 57, 1655 – 1666 (2009).

  11. V. V. Khasanov, G. L. Ryzhova, and E. V. Mal?tseva, Khim. Rastit. Syr’ya, 3, 63 – 75 (2004).

  12. V. L. Singleton and J. A. Rossi, Am. J. Enol. Vitic., 16, 144 – 158 (1965).

    CAS  Google Scholar 

  13. G. Miliauskas, P. R. Venskutonis, and T. A. van Beck, Food Chem., 85, 231 – 237 (2004).

    Article  CAS  Google Scholar 

  14. I. F. F. Benzie and J. J. Strain, Anal. Biochem., 239, 70 – 76 (1996).

    Article  CAS  PubMed  Google Scholar 

  15. R. Re, N. Pellegrini, A. Proteggente, et al., Free Radical Biol. Med., 26, 1231 – 1237 (1999).

    Article  CAS  Google Scholar 

  16. I. I. Koleva, T. A. van Beek, J. P. H. Linssen, et al., Phytochem. Anal., 13, 8 – 17 (2002).

    Article  CAS  PubMed  Google Scholar 

  17. C. A. Rice-Evans, N. J. Miller, and G. Paganga, Free Radical Biol. Med., 20, 933 – 956 (1996).

    Article  CAS  Google Scholar 

  18. E. Middleton, C. Kandaswami, and T. Theoharides, Pharmacol. Rev., 52, 673 – 675 (2000).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. M. A. Aitkhozhin Institute of Molecular Biology and Biochemistry, Ministry of Education and Science, Republic of Kazakhstan Science Committee, Almaty, 050012, Kazakhstan

    O. A. Sapko, O. V. Chebonenko, A. Sh. Utarbaeva, A. Zh. Amirkulova & A. K. Tursunova

Authors
  1. O. A. Sapko
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. O. V. Chebonenko
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. Sh. Utarbaeva
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. Zh. Amirkulova
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. A. K. Tursunova
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to A. Sh. Utarbaeva.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 50, No. 9, pp. 33 – 37, September, 2016.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sapko, O.A., Chebonenko, O.V., Utarbaeva, A.S. et al. Antioxidant Activity of Medicinal Plants from Southeastern Kazakhstan. Pharm Chem J 50, 603–607 (2016). https://doi.org/10.1007/s11094-016-1499-6

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11094-016-1499-6

Keywords

Search

Navigation