We explored the mechanism underlying the improvement of tolerance to exercise-heat stress through physical training at a moderate temperature. Rats were randomly divided into an aerobic exercise (AE) group and a control (C) group. Rats in the former group were subjected during 5 weeks for AE in a cool environment (20°C). The oxidative damage level in the brain to AE rats after both 1-h-long heat exposure and exhaustive exercise in heat and the rate of core temperature rise were lower than those in the control (P < 0.05). The expression level of HSP70 in the motor cortex and the exhaustion time in group AE were found to be significantly greater compared to those in group C (P < 0.05). Our results indicate that the enhanced expression of HSP70 may be an important factor for physical training in a cool environment, and this factor improves tolerance to exercise-heat stress.
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Wang, D., Ripley-Gonzalez, J.W. & Hu, Y. Aerobic Physical Training Protects the Rat Brain Against Exercise-Heat Related Oxidative Damage through the Increased Expression of HSP70. Neurophysiology 51, 66–71 (2019). https://doi.org/10.1007/s11062-019-09794-9
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DOI: https://doi.org/10.1007/s11062-019-09794-9