Skip to main content
SpringerLink
Log in

Recovery of Speech Functions in Patients with Poststroke Aphasia Depending on the Severity of Atherosclerotic Lesions of the Cerebral Arteries

  • Published:
Neuroscience and Behavioral Physiology Aims and scope Submit manuscript

Objective. To study the effects of stenosing lesions of the carotid arteries on recovery of aphatic impairments during the acute period of stroke. Materials and methods. The case histories of 253 patients (median age 58 [52; 63] years) with acute left-hemisphere ischemic and hemorrhagic stroke including motor or sensorimotor aphasia were analyzed. The severity of atherosclerotic lesions to the brachiocephalic arteries was evaluated by color duplex scanning, whose results were used to divide patients into three groups: group 1, without stenosis of the extracranial arteries; group 2, with carotid artery stenosis of <50% of the vessel lumen; and group 3, with >50% stenosis of the carotid arteries. Results. The presence of stenosing lesions of the extracranial arteries in patients with aphasia narrowing the vessel lumen by more than 50% (group 3) significantly (p = 0.0001) degraded prognoses for recovery of speech functions, while stenosis of less than 50% (groups 1 and 2) had no significant influence on the prognosis for speech rehabilitation. Conclusions. Severe atherosclerosis of the carotid arteries had adverse influences on the dynamics of speech recovery in patients during the acute period of stroke.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. L. V. Stakhovskaya and S. V. Kotov (eds.), Stroke. Guidelines for Doctors, MIA, Moscow (2014).

    Google Scholar 

  2. E. Olesen, A. Gustavsson, M. Svensson, et al., “Economy costs of brain disease in Europe,” Ural. Med. Zh., 5, 5–12 (2012).

    Google Scholar 

  3. N. A. Shamalov and I. M. Shetova, “Combined cytoprotection in the treatment of impairments to the cerebral circulation,” Effektiv. Farmakoter., No. 3, 12–14 (2011).

    Google Scholar 

  4. E. I. Gusev, V. I. Skvortsova, V. V. Kilikovskii, et al., “The problem of stroke in the Russian Federation,” Kach. Zhizni, 2, No. 13, 10–14 (2006).

    Google Scholar 

  5. E. I. Gusev, A. M. Konovalov, V. I. Skvortsovaya, and A. B. Gekht (eds.), Neurology. National Guidelines, GEOTAR-Media, Moscow (2012).

    Google Scholar 

  6. M. K. Burlakova, Speech and Aphasia, Meditsina, Moscow (1997).

    Google Scholar 

  7. D. O’Leary, J. Polak, R. Kronmal, et al., “Distribution and correlates of sonographically detected carotid artery disease in the cardiovascular health study,” Stroke, 23, No. 12, 1752–1760 (1992), doi: https://doi.org/10.1161/01.str.23.12.1752.

    Article  PubMed  Google Scholar 

  8. A. S. Kadykov, L. S. Manvelov, and N. V. Shakhparonova, Chronic Vascular Diseases of the Brain: Dyscirculatory Encephalopathy. Guidelines for Doctors, GEOTAR-Media, Moscow (2014), 3rd ed.

  9. V. V. Kuznetsov, N. I. Gulyaev, and I. M. Pavlovich, “Atherosclerosis and dyslipidemia, Part III. Clinical signs, diagnosis, principles of prophylaxis and treatment of atherosclerosis,” Nov. St. Petersb. Vrach. Vedom., No. 3, 9–25 (2012).

  10. I. G. Uchkin, A. G. Bagdasaryan, and E. S. Aleksandrova, “ The role of duplex ultrasound scanning in the diagnosis of carotid stenoses,” Consilium Medicum, 9, 38–42 (2010).

    Google Scholar 

  11. S. G. Zhdanova, P. R. Kamchatnov, I. S. Aliev, et al., “Prognostic significance of measures of cerebral hemodynamics in patients with carotid ischemic stroke,” Zh. Nevrol. Psikhiat., 113, No. 3–2, 21–24 (2013).

    CAS  Google Scholar 

  12. A. V. Pokrovskii (ed.), Clinical Angiology. Guidelines, Meditsina, Moscow (2004), Vol. 1.

  13. L. S. Manvelov, and A. S. Kadykov (eds.), Early Clinical Forms of Cerebrovascular Diseases. Guidelines for Doctors, GEOTAR-Media, Moscow (2014).

    Google Scholar 

  14. M. V. Putilina, “Neuroplasticity as the basis for the early rehabilitation of patients after stroke,” Zh. Nevrol. Psikhiat., 111, No. 12, 64–69 (2011).

    CAS  Google Scholar 

  15. S. A. Gulyaev, A. V. Ovchinnikov, and I. V. Arkhipenko, “’Asymptomatic’ stenoses of the major arteries of the head and their influences on brain bioelectrical activity,” Trudn. Patsient, 10, No. 12, 18–21 (2012).

    Google Scholar 

  16. A. V. Maksimov, Yu. E. Teregulov, E. A. Gaisina, and M. V. Plotnikov, “Age and gender characteristics of pathology of the internal carotid arteries,” Prakt. Med., 80, No. 4–2, 70–73 (2014).

    Google Scholar 

  17. V. I. Tseluiko and I. V. Kuznetsov, “Diagnosis of atherosclerotic lesions of the carotid arteries and peripheral arteries of the lower limbs in cardiology practice,” Lіki Ukraїni, 5, No. 161, 8–12 (2012).

    Google Scholar 

  18. E. B. Kuperberg, A. N. Bakulev (eds.), Clinical Doppler Investigations of Lesioned Arteries in the Brain and Limbs. Therapeutic Guidelines, NTsSSKh RAMN, Moscow (1997).

    Google Scholar 

  19. B. M. Lipovetskii, Dyslipidemia and Atherosclerosis and Their Links with Ischemic Disease of the Heart and Brain. Guidelines for Doctors and Medical Students, Eko-Vektor, St. Petersburg (2012).

    Google Scholar 

  20. B. M. Lipovetskii, Atherosclerosis and Its Complications of the Heart, Brain, and Aorta. Guidelines for Doctors, SpetsLit, St. Petersburg (2008).

    Google Scholar 

  21. G. von Reutern, M. Goertler, N. Bornstein, et al., “Grading carotid stenosis using ultrasonic methods,” Stroke, 43, 916–921 (2012), doi: https://doi.org/10.1161/strokeaha.111.636084.

    Article  Google Scholar 

  22. R. Lazar, B. Minzer, D. Antoniello, et al., “Improvement in aphasia scores after stroke is well predicted by initial severity,” Stroke, 41, 1485–1488 (2010), doi: https://doi.org/10.1161/strokeaha.109.577338.

    Article  PubMed  PubMed Central  Google Scholar 

  23. R. Pedersen, K. Vinterb, and T. Olsen, “Aphasia after stroke: type, severity and prognosis,” Cerebrovasc. Dis., 17, No. 1, 35–43 (2004), doi: https://doi.org/10.1159/000073896.

    Article  PubMed  Google Scholar 

  24. O. Godefroy, C. Dubois, B. Debachy, et al., “Vascular aphasias. Main characteristics of patients hospitalized in acute stroke units,” Stroke, 33, No. 3, 702–705 (2002), doi: https://doi.org/10.1161/hs0302.103653.

    Article  CAS  PubMed  Google Scholar 

  25. S. Engelter, M. Gostynski, S. Papa, et al., “Epidemiology of aphasia attributable to first ischemic stroke: incidence, severity, fluency, etiology, and thrombolysis,” Stroke, 37, No. 6, 1379–1384 (2006), doi: https://doi.org/10.1161/01.str.0000221815.64093.8c.

    Article  PubMed  Google Scholar 

  26. A. Laska, A. Hellblom, V. Murray, et al., “Aphasia in acute stroke and relation to outcome,” J. Int. Med., 249, No. 5, 413–422 (2001), doi: https://doi.org/10.1046/j.1365-2796.2001.00812.x.

    Article  CAS  Google Scholar 

  27. A. V. Belopasova, A. S. Kadykov, N. V. Shakhparonova, and E. S. Berdnikovich, “Brain lesion focus volume – the main factor affecting the nature and dynamics of recovery of poststroke aphasia,” in: Proc. 10th All-Russ. Congr. of Neurologists with International Participation, Nizhnii Novgorod (2012), pp. 35–37.

  28. A. V. Belopasova, R. N. Konovalov, E. I. Kremneva, et al., “Factors affecting the recovery of speech after stroke,” in: Proc. 3rd Int. Neurorehabilitation Congr., Moscow (2011).

  29. J. Kim, T. J. Song, D. Song, et al., “Nonrelevant cerebral atherosclerosis is a strong prognostic factor in acute cerebral infarction,” Stroke, 44, No. 7, 2013–2015 (2013), doi: https://doi.org/10.1161/strokeaha.113.001111.

    Article  PubMed  Google Scholar 

  30. A. S. Kadykov and N. V. Shakhparonova, “Rehabilitation of poststroke patients. The role of medication therapy,” Med. Sovet, No. 4, 92–98 (2013).

Download references

Author information

Authors and Affiliations

  1. Kemerovo State Medical Academy, Kemerovo, Russia

    M. N. Safronova & A. V. Kovalenko

  2. Kemerovo Cardiology Dispensary, Kemerovo, Russia

    O. A. Mizyurkina & A. V. Kovalenko

  3. Research Institute of Complex Problems in Cardiovascular Diseases, Kemerovo, Russia

    A. V. Kovalenko & O. L. Barbarash

  4. Regional Clinical Hospital for Veterans of Wars, Kemerovo, Russia

    M. N. Safronova

Authors
  1. M. N. Safronova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. O. A. Mizyurkina
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. V. Kovalenko
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. O. L. Barbarash
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to M. N. Safronova.

Additional information

Translated from Zhurnal Nevrologii i Psikhiatrii imeni S. S. Korsakova, Vol. 116, No. 3, Iss. II, Stroke, pp. 31–35, March, 2016.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Safronova, M.N., Mizyurkina, O.A., Kovalenko, A.V. et al. Recovery of Speech Functions in Patients with Poststroke Aphasia Depending on the Severity of Atherosclerotic Lesions of the Cerebral Arteries. Neurosci Behav Physi 47, 836–840 (2017). https://doi.org/10.1007/s11055-017-0478-z

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11055-017-0478-z

Keywords

Search

Navigation