Skip to main content
Log in

Tooth instance segmentation from cone-beam CT images through point-based detection and Gaussian disentanglement

  • Published:
Multimedia Tools and Applications Aims and scope Submit manuscript

Abstract

Individual tooth segmentation and identification from cone-beam computed tomography images are preoperative prerequisites for orthodontic treatments. Instance segmentation methods using convolutional neural networks have demonstrated ground-breaking results on individual tooth segmentation tasks, and are used in various medical imaging applications. While point-based detection networks achieve superior results on dental images, it is still a challenging task to distinguish adjacent teeth because of their similar topologies and proximate nature. In this study, we propose a point-based tooth localization network that effectively disentangles each individual tooth based on a Gaussian disentanglement objective function. The proposed network first performs heatmap regression accompanied by box regression for all the anatomical teeth. A novel Gaussian disentanglement penalty is employed by minimizing the sum of the pixel-wise multiplication of the heatmaps for all adjacent teeth pairs. Subsequently, individual tooth segmentation is performed by converting a pixel-wise labeling task to a distance map regression task to minimize false positives in adjacent regions of the teeth. Experimental results demonstrate that the proposed algorithm outperforms state-of-the-art approaches by increasing the average precision of detection by 9.1%, which results in a high performance in terms of individual tooth segmentation. The primary significance of the proposed method is two-fold: (1) the introduction of a point-based tooth detection framework that does not require additional classification and (2) the design of a novel loss function that effectively separates Gaussian distributions based on heatmap responses in the point-based detection framework.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Similar content being viewed by others

References

  1. Çiçek Ö, Abdulkadir A, Lienkamp SS, Brox T, Ronneberger O (2016) 3d u-net: learning dense volumetric segmentation from sparse annotation. In: International conference on medical image computing computer-assisted intervention. Springer, Berlin, pp 424–432

  2. Chung M, Lee M, Park S, Lee M, Lee CE, Lee J, Shin Y-G (2020) Individual tooth detection and identification from dental panoramic x-ray images via point-wise localization and distance regularization. Artif Intell Med 111:101996

    Article  Google Scholar 

  3. Chung M, Lee M, Hong J, Park S, Lee J, Lee J, Yang I-H, Lee J, Shin Y-G (2020) Pose-aware instance segmentation framework from cone beam ct images for tooth segmentation. Comput Biol Med 120:103720

  4. Cui Z, Li C, Wang W (2019) Toothnet: Automatic tooth instance segmentation and identification from cone beam ctimages. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp 6368–6377

  5. Dalal N, Triggs B (2005) Histograms of oriented gradients for human detection. In: 2005 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR’05), vol 1. IEEE, pp 886–893

  6. Duan K, Bai S, Xie L, Qi H, Huang Q, Tian Q (2019) Centernet: Keypoint triplets for object detection. In: Proceedings of the IEEE/CVF International Conference on Computer Vision, pp 6569–6578

  7. Girshick R, Donahue J, Darrell T, Malik J (2014) Rich feature hierarchies for accurate object detection and semantic segmen-tation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp 580–587

  8. He K, Gkioxari G (2017) Piotr Dollár, and Ross Girshick. Mask r-cnn. In: Proceedings of the IEEE International Conference on Computer Vision, pp 2961–2969

  9. Law H, Deng J (2018) Cornernet: Detecting objects as paired keypoints. In: Proceedings of the European Conference on Computer Vision(ECCV), pp 734–750

  10. Lee J-H, Han S-S, Kim YH, Lee C, Kim I (2020) Application of a fully deep convolutional neural network to the automation of tooth segmentation on panoramic radiographs. Oral Surg Oral Med Oral Pathol Oral Radiol 129(6):635–642

  11. Lienhart R, Maydt J (2002) An extended set of haar-like features for rapid object detection. In: Proceedings. International Conferenceon Image Processing, vol 1. IEEE, pp I–I

  12. Long J, Shelhamer E, Darrell T (2015) Fully convolutional networks for semantic segmentation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp 3431–3440

  13. Lowe DG (2004) Distinctive image features from scale-invariant keypoints. Int J Comput Vision 60(2):91–110

    Article  Google Scholar 

  14. Miki Y, Muramatsu C, Hayashi T, Zhou X, Hara T, Katsumata A, Fujita H (2017) Classification of teeth in cone-beam CT using deep convolutional neural network. Comput Biol Med 80:24–29

    Article  Google Scholar 

  15. Newell A, Yang K, Deng J (2016) Stacked hourglass networks for human pose estimation. In: European Conference on Computer Vision. Springer, Berlin, pp 483–499

  16. Pedro F, Felzenszwalb RB, Girshick D, McAllester, Ramanan D (2009) Object detection with discriminatively trained part-basedmodels. IEEE Trans Pattern Anal Mach Intell 32(9):1627–1645

    Google Scholar 

  17. Redmon J, Farhadi A (2018) Yolov3: An incremental improvement. arXiv preprint arXiv:1804.02767

  18. Redmon J, Farhadi A (2017) Yolo9000: better, faster, stronger. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp 7263–7271

  19. Redmon J, Divvala S, Girshick R, Farhadi A (2016) You only look once: Unified, real-time object detection. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp 779–788

  20. Ren R, He K, Girshick R, Sun J (2015) Faster r-cnn: Towards real-time object detection with region proposal networks. In: Advances in Neural Information Processing Systems, pp 91–99

  21. Ronneberger O, Fischer P, Brox T (2015) U-net: Convolutional networks for biomedical image segmentation. In: International Conference on Medical Image Computing and Computer-Assisted Intervention. Springer, Berlin, pp 234–241

  22. Rosenfeld A, Pfaltz JL (1968) Distance functions on digital pictures. Pattern Recogn 1(1):33–61

    Article  MathSciNet  Google Scholar 

  23. Tuzoff DV, Tuzova LN, Bornstein M, Krasnov AS, Kharchenko MA, Nikolenko SI, Sveshnikov MM, Bednenko GB (2019) Tooth detection and numbering in panoramic radiographs using convolutional neural networks. Dento Maxillo Fac Radiol 48(4):20180051

    Article  Google Scholar 

  24. Van Ginneken B, Ter Romeny BM, Viergever MA (2001) Computer-aided diagnosis in chest radiography: a survey. IEEE Trans Med Imaging 20(12):1228–1241

    Article  Google Scholar 

  25. Wu K, Chen L, Li J, Zhou Y (2014) Tooth segmentation on dental meshes using morphologic skeleton. Comput Graph 38:199–211

  26. Xu X, Liu C, Zheng Y (2019) 3D tooth segmentation and labeling using deep convolutional neural networks. IEEE Trans Vis Comput Graph 25(7):2336–2348. https://doi.org/10.1109/TVCG.2018.2839685

  27. Zhao Z-Q, Zheng P, Xu Shou-tao, Wu X (2019) Object detection with deep learning: A review. IEEE Trans Neural Networks Learn Syst 30(11):3212–3232

    Article  Google Scholar 

  28. Zhou X, Wang D, Krähenbühl P (2019) Objects as points. arXiv preprint arXiv:1904.07850

Download references

Acknowledgements

This work was supported by Institute of Information & communications Technology Planning & Evaluation (IITP) grant funded by the Korea government(MSIT) (No.2021-0-00511, Robust AI and Distributed Attack Detection for Edge AI Security).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Minyoung Chung.

Ethics declarations

Conflict of interest

None declared. 

Author agreement

All authors including Jusang Lee, Minyoung Chung, Minkyung Lee, and Yeong-Gil Shin agreed the submission of this manuscript.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lee, J., Chung, M., Lee, M. et al. Tooth instance segmentation from cone-beam CT images through point-based detection and Gaussian disentanglement. Multimed Tools Appl 81, 18327–18342 (2022). https://doi.org/10.1007/s11042-022-12524-9

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11042-022-12524-9

Keywords

Navigation