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Analysis of Normative Support for Measurements of Catalytic Activity for Biologically and Chemically Active Substances

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Measurement Techniques Aims and scope

We analyze the normative and methodological support for measurements of catalytic activity for biological and chemical substances. We consider the results of work by experts at the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC), who have studied optimized conditions for measuring catalytic activity concentration of individual enzymes in human blood serum. We have defined the problem of developing a reference standard for the unit of catalytic activity.

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References

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  3. “IFCC Primary Reference Procedures for the Measurement of Catalytic Activity Concentrations of Enzymes at 37°C. Part 1. The Concept of Reference Procedures for the Measurement of Catalytic Activity Concentrations of Enzymes,” Clin. Chem. Lab. Med., 40, No. 6, 631–634 (2002).

  4. GOST R ISO 18153-2006, In Vitro Diagnostic Medical Devices. Measurement of Quantities in Biological Samples. Metrological Traceability of Values for Catalytic Concentration of Enzymes Assigned to Calibrators and Control Materials.

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Correspondence to Yu. A. Kudeyarov.

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Translated from Metrologiya, No. 3, pp. 36–45, July–September, 2016.

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Kudeyarov, Y.A., Kulyabina, E.V., Melkova, O.N. et al. Analysis of Normative Support for Measurements of Catalytic Activity for Biologically and Chemically Active Substances. Meas Tech 59, 1007–1012 (2016). https://doi.org/10.1007/s11018-016-1084-0

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  • DOI: https://doi.org/10.1007/s11018-016-1084-0

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