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Preparation and ultraviolet sunscreen properties of organic-silica hybrid particles encapsulated benzophenone-3

  • Original Paper: Sol-gel and hybrid materials with surface modification for applications
  • Published:
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Abstract

In the present study, ultraviolet (UV) absorptive organic-silica hybrid particles with naturally UV absorption, 2-hydroxy-N-[3-(triethoxysilyl)propyl]benzamide (2-HTESC), have been synthesized through the reaction of 3-aminopropyltriethoxysilane (APTES) and salicylic acid. The chemical structure of 2-HTESC monomer was characterized by FT-IR and 1H NMR spectra. Since benzophenone-3(BP-3) was often served as an organic UV filter in sunscreen formulations, yet its allowable load was limited to 6% in the formulations of lotions and creams. Therefore, our goal was to prepare an absorber (2-HTESC) with its own UV absorption to trap BP-3 to construct a target sunscreen BP-3@P2-HTESC composite material with dual sun protection functions, while also reducing the leakage of BP-3 into emulsion and cream. By comparing the two reactions, it was found that the self-catalytic reaction was superior to the alkali-catalyzed reaction. BP-3 was successfully loaded into P2-HTESC molecular network by hydrolytic polycondensation under self-catalytic condition, and the maximum encapsulation rate reached 68%. In addition, BP-3@P2-HTESC-1 sunscreen under self-catalytic reaction showed good UV absorption, excellent thermoresistance, and less controlled release of BP-3 organic molecules to match the maximum allowable amount of BP-3 in sunscreen products.

Graphical abstract

Highlights

  • Organic-silica hybrid 2-HTESC monomer with natural UV absorption is synthesized via the self-catalyzed synthesis based on APTES and salicylic acid.

  • The target composite sunscreen BP-3@P2-HTESC has been synthesized by hydrolysis-polycondensation reaction.

  • BP-3@P2-HTESC sunscreen shows good UV absorption, excellent thermoresistance, and the controlled little release of BP-3 from P2-HTESC carrier.

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Acknowledgements

We gratefully acknowledge the National Natural Science Foundation of China (22078159, 21003074, U19B2001, 21878159, 21706131 and 21908092); Natural Science Foundation of Jiangsu Province (BK20181378 and BK20131407), and Open Fund of Beijing Advanced Innovation Center for Food Nutrition and Human Health (20161002).

Author contributions

HF: Conceptualization, Validation, Investigation, Writing-original draft, Visualization; HS: Investigation, Visualization, Revision; SY: Investigation, Writing-original draft; LW: Investigation, Revision; JW: Methodology, Resources; Resources, Funding acquisition. MH: Conceptualization, Writing-original draft, Resources, Project administration, Funding acquisition.

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Authors and Affiliations

  1. College of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing, 210009, China

    Hongfang Fan, Hualei Shi, Shuo Yao, Lin Wang, Jianqiang Wang & Mingjuan Han

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  1. Hongfang Fan
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  2. Hualei Shi
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Correspondence to Jianqiang Wang or Mingjuan Han.

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Fan, H., Shi, H., Yao, S. et al. Preparation and ultraviolet sunscreen properties of organic-silica hybrid particles encapsulated benzophenone-3. J Sol-Gel Sci Technol 101, 468–476 (2022). https://doi.org/10.1007/s10971-022-05723-1

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  • DOI: https://doi.org/10.1007/s10971-022-05723-1

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