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Curcuma longa tuber extract mediated synthesis of hydroxyapatite nanorods using biowaste as a calcium source for the treatment of bone infections

  • Original Paper: Nano-structured materials (particles, fibers, colloids, composites, etc.)
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Abstract

Bone fillers based on hydroxyapatite (HAp) having antimicrobial activity are extensively applied for treatment of bone-related inflammation created by infectious micro-organisms. We report the biogenic preparation of HAp nanorods with the aid of Curcuma longa tuber extract as solvent and eggshell biowaste as a calcium source. The prepared powder was analyzed by various analytical tools to explore the phase purity and morphological feature. The obtained results indicate that the prepared powder was magnesium (Mg) and carbonate (CO32−) containing HAp nanorods having nanocrystalline characteristics. Further, the prepared HAp nanorods significantly hinder the growth of E. coli and S. aureus. Comparative studies were also carried out with HAp prepared using water as solvent. The obtained results clearly shows that developed method can be a prospective approach to acquire precursor material for making bone fillers with antibacterial activity.

Hydroxyapatite (HAp) nanorods with antibacterial activity were prepared by simple biogenic synthesis using Curcuma longa tuber extract, eggshell, and Na2HPO4 as the source for the treatment of bone infections in orthopedics.

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Acknowledgements

G. Suresh Kumar would like to express his sincere thanks to University Grant Commission, India for financial support through minor research project scheme (File No: 4-4/2015-16 (MRP/UGC SERO)). The work was carried out with financial support from the Ministry of Education and Science of the Russian Federation in the framework of increase Competitiveness Program of NUST ‘MISIS’ (№ К3-2017-055), implemented by a governmental decree dated 16th of March 2013, N 211.

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Authors and Affiliations

  1. Department of Physics, K.S. Rangasamy College of Arts and Science (Autonomous), Tiruchengode, Tamil Nadu, 637215, India

    Govindan Suresh Kumar

  2. Department of Physics, Periyar University, Salem, Tamil Nadu, 636011, India

    Devaraj Muthu, Sekar Karthi & Easwaradas Kreedapathy Girija

  3. Department of Functional Nanosystems and High-Temperature Materials, National University of Science and Technology “MISiS,” Leninskiy Pr. 4, Moscow, 119049, Russia

    Gopalu Karunakaran & Denis Kuznetsov

  4. Department of Biotechnology, K.S. Rangasamy College of Arts and Science (Autonomous), Tiruchengode, Tamil Nadu, 637215, India

    Gopalu Karunakaran

Authors
  1. Govindan Suresh Kumar
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  2. Devaraj Muthu
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  3. Gopalu Karunakaran
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  4. Sekar Karthi
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  5. Easwaradas Kreedapathy Girija
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  6. Denis Kuznetsov
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Correspondence to Govindan Suresh Kumar.

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Highlights

  • Novel method to obtain biomaterials with antibacterial activity

  • Bone-mineral-like material for the treatment of bone infections

  • Economic and environmental benefits due to biowaste recovery

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Kumar, G.S., Muthu, D., Karunakaran, G. et al. Curcuma longa tuber extract mediated synthesis of hydroxyapatite nanorods using biowaste as a calcium source for the treatment of bone infections. J Sol-Gel Sci Technol 86, 610–616 (2018). https://doi.org/10.1007/s10971-018-4670-6

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  • DOI: https://doi.org/10.1007/s10971-018-4670-6

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