Skip to main content
SpringerLink
Log in

Determination of 55Fe in urine by liquid scintillation counting

  • Published:
Journal of Radioanalytical and Nuclear Chemistry Aims and scope Submit manuscript

Abstract

A new method has been developed to measure Iron-55 (55Fe) in urine samples, which could be used for dose assessment of 55Fe in an accidental exposure. 55Fe was effectively precipitated from 1 litre of urine by bringing the sample to 2M NaOH. Potential interferences for 55Fe (e.g., Cr, Co, Ni, Mn, Zn and Mo) were removed by anion exchange chromatography. The Fe recovery was measured by UV–Vis absorption spectroscopy and 55Fe was determined by liquid scintillation counting. The method was validated using spiked samples.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

References

  1. Holden NE (2013) CRC handbook of chemistry and physics. http://www.hbcpnetbase.com/. Accessed June 2014

  2. Evans JC, Lepel EL, Sanders RW, Wilkerson CL, Silker W, Thomas CW, Abel KH, Robertson DR (1984) Long-lived activation products in reactor materials. Pacific Northwest Laboratory, Richland

  3. Brechignac F, Deville-Cavelin G (2002) Fiche radionucléide 59Fe et environnement. IRSN, Fontenay-aux-Roses

    Google Scholar 

  4. Warwick PE, Croudace IW (2006) Anal Chim Acta 567:277–285

    Article  CAS  Google Scholar 

  5. Hou X, Østergaard LF, Nielsen SP (2004) Anal Chim Acta 535:297–307

    Article  Google Scholar 

  6. König W, Schupfner R, Schüttelkopf H (1995) J Radioanal Nucl Chem 193:119–125

    Article  Google Scholar 

  7. Nielsen JM (1960) The radiochemistry of iron. N.R.C, Washington

    Google Scholar 

  8. Collier CG, Stradling GN, Foster PP, Hodgson A (1994) Radiat Prot Dosim 53:173–177

    CAS  Google Scholar 

  9. Bukhave K, Sorensen AD, Hansen MA (2001) J Trace Elem Med Biol 15:56–58

    Article  CAS  Google Scholar 

  10. ICRP Publication 69 (1995) Age-dependent doses to members of the public from intake of radionuclides: part 3 ingestion dose coefficients. Pergamon, Oxford

  11. ICRP Publication 23 (1975) Report on the task group on reference man. International commission on radiological protection. Pergamon, Oxford

    Google Scholar 

  12. Jäggi M, Rüthi M, Eikenberg J (2008) Method for 55Fe and 63Ni determination by LSC in radioactive waste. In: Proceedings of the LSC conference, Davos

  13. Grahek Ž (2006) Rožmari Mačefat M. J Radioanal Nucl Chem 267:131–137

    Article  CAS  Google Scholar 

  14. Dai X, Kramer-Tremblay S (2014) Anal Chem 86(11):5441–5447

    Article  CAS  Google Scholar 

  15. Taddei MHT, Macacini JF, Vicente R, Marumo JT, Sakata SK, Terremoto LAA (2013) J Radioanal Nucl Chem 295:2267–2272

    Article  CAS  Google Scholar 

  16. Mikelic L, Orescanin V, Lulic S (2007) Nucl Instrum Methods Phys Res Sect B 263:95–98

    Article  CAS  Google Scholar 

  17. Geckeis H, Hentschel D, Jensen D, Görtzen A, Kerner N (1997) J Anal Chem 357:864–869

    Article  CAS  Google Scholar 

  18. Iron-55 in Water (2001) Analytical Procedures. Eichrom Tecnologies, LLC, Lisle

  19. Gascó C, Navarrob N, Alvarezb A, Herasa C, Suañeza A (2008) The difficulties of measuring 55Fe and 63Ni in environmental samples. Department of Radiation Protection, CIEMAT, Madrid

    Google Scholar 

  20. Vajda N, Molnár S, Osváth S (2005) Extraction chromatography and liquid scintillation counting for the analysis of long-lived radionuclides. In: Proceedings of the LSC conference, Davos

  21. Priya S, Gopalakrishnan RK, Goswami A (2014) J Radioanal Nucl Chem. doi:10.1007/s10967-014-3190-2

    Google Scholar 

  22. Razdolescua AC, Cassette PH, Sahagia M (2008) Appl Radiat Isot 66:750–755

    Article  Google Scholar 

  23. El-kot AM (1990) Isot Environ Health Stud 26(10):499–502

    Article  CAS  Google Scholar 

  24. Cregan SP, Leon JW, Linauskas SH (1993) Bioassays techniques for 55Fe in urine samples, AECL internal report

  25. Putnam DF (1971) Composition and concentrative properties of human urine. N.A.S.A, Washington

    Google Scholar 

  26. Currie LA (1968) Anal Chem 40:586–593

    Article  CAS  Google Scholar 

  27. Guerin N, Dai X (2014) Anal Chem 86:6026–6031

    Article  CAS  Google Scholar 

  28. Kolthoff IM, Sandell EB (1945) Textbook of quantitative inorganic analysis. The Macmillan Company, New York

    Google Scholar 

  29. Silva AMN, Kong XL, Parkin MC, Cammack R, Hider RC (2009) Dalton Trans 40:8616–8625

    Article  Google Scholar 

  30. Rue EL, Bruland KW (1995) Mar Chem 50:117–138

    Article  CAS  Google Scholar 

  31. Schweitzer GK, Pesterfield LL (2010) The aqueous chemistry of the elements. Oxford University Press, New York

    Google Scholar 

  32. Sato K, Hyodo M, Takagi J, Aoki M, Noyori R (2000) Tetrahedron Lett 9:1439–1442

    Article  Google Scholar 

  33. Jain AK, Kumar M, Kumar D (2014) Pharm Chem 6:187–193

    Google Scholar 

  34. Pol UN, Yamgar RS, Dodwad SS (1997) Asian J Chem 9:58–62

    CAS  Google Scholar 

  35. Mathew A, Panda JK (2012) Int Res J Pure Appl Chem 2:196–210

    Article  CAS  Google Scholar 

  36. Theis Thomas L, Singer Philip C (1974) Environ Sci Technol 8:569–573

    Article  CAS  Google Scholar 

  37. Greenwood NN, Earnshaw A (2003) Chemistry of the elements, 2nd edn. Elsevier Butterworth-Heinemann, Oxford

    Google Scholar 

  38. Kraus KA, Nelson F (1995) Distribution coefficients of the elements on strong anion exchange resins in HCl. In: Proceedings of 1st international conference on peaceful uses atomic energy,7,118

  39. Klueh RL (2004) Elevated-temperature ferritic and martensitic steels and their application to future nuclear reactors. Oak Ridge National Laboratory, Oak Ridge

    Google Scholar 

  40. Lee BS, Kim MC, Yoon JH, Hong JH (2010) Int J Press Vessel Pip 87:74–80

    Article  CAS  Google Scholar 

  41. Kim KY, Kim HY, Rho GH, Sohn DS (2011) J Nucl Sci Technol 1:24–27

    Google Scholar 

  42. Performance criteria for radiobioassay N13.30 (1996) ANSI/HPS, New York

  43. Mughabghab SF (2003) Thermal neutron capture cross sections resonance integrals and G-factors. I.A.E.A., Vienna

    Google Scholar 

Download references

Acknowledgments

This research was funded by the AECL Research and Development program. The authors wish to thank the Dosimetry Services Laboratory staff of Chalk River Laboratories for their assistance with this work.

Author information

Authors and Affiliations

  1. Radiological Protection Research and Instrumentation Branch, Canadian Nuclear Laboratories, Building 513, Chalk River, ON, K0J 1J0, Canada

    Nicolas Guérin & Xiongxin Dai

Authors
  1. Nicolas Guérin
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Xiongxin Dai
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Nicolas Guérin.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Guérin, N., Dai, X. Determination of 55Fe in urine by liquid scintillation counting. J Radioanal Nucl Chem 304, 1059–1069 (2015). https://doi.org/10.1007/s10967-015-4012-x

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10967-015-4012-x

Keywords

Search

Navigation