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South Asian Health: Inflammation, Infection, Exposure, and the Human Microbiome

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Abstract

This paper presents the results of the literature review conducted for the working group topic on inflammation, infection, exposure, and the human microbiome. Infection and chronic inflammation can elevate risk for cardiovascular disease and cancer. Environmental exposures common among South Asian (SA) subgroups, such as arsenic exposure among Bangladeshis and particulate matter air pollution among taxi drivers, also pose risks. This review explores the effects of exposure to arsenic and particulate matter, as well as other infections common among SAs, including human papillomavirus (HPV) and hepatitis B/C infection. Emerging research on the human microbiome, and the effect of microbiome changes on obesity and diabetes risk among SAs are also explored.

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Acknowledgements

This publication was supported by the National Institute on Minority Health and Health Disparities of the National Institutes of Health under Award Number R13 MD007147- 01A1 and National Cancer Institute of the National Institutes of Health under Award Number P30 CA008748. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. SAHI staff would like to thank the Steering Committee members, all working group co-chairs, the Memorial Sloan Kettering Cancer Center Library, Rohini Rau-Murthy and the SAHI interns for their assistance in assembling this document.

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Authors and Affiliations

  1. Department of Psychiatry and Behavioral Sciences, Immigrant Health and Cancer Disparities Service, Memorial Sloan Kettering Cancer Center, 485 Lexington Avenue, 2nd Floor, New York, NY, 10017, USA

    Jennifer Leng & Francesca Gany

  2. Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, USA

    Jennifer Leng & Francesca Gany

  3. Department of Healthcare Policy and Research, Weill Cornell Medical College, 1300 York Avenue, New York, NY, USA

    Jennifer Leng & Francesca Gany

  4. Department of Medicine, Icahn School of Medicine at the Mount Sinai Medical Center, 1468 Madison Avenue, New York, NY, USA

    Ponni Peruluswami

  5. The Earth Institute, Columbia University, 2910 Broadway, New York, NY, USA

    Sehrish Bari

  6. Robert Wood Johnson Medical School, South Asian Total Health Initiative, Rutgers School of Public Health, Rutgers, The State University of New Jersey, 1 Robert Wood Johnson Place, New Brunswick, NJ, USA

    Sunanda Gaur

  7. Cardiology Department, Queens Hospital Center, 82-68 164th Street, Jamaica, New York, NY, USA

    Farshid Radparvar

  8. Department of Environmental Health Sciences, Columbia University, 722 W 168th Street, New York, NY, USA

    Faruque Parvez

  9. Department of Population Health, Department of Environmental Medicine, New York University School of Medicine, 550 1st Avenue, New York, NY, USA

    Yu Chen

  10. The Warren Alpert Medical School, The Brown Human Rights Asylum Clinic (BHRAC), Brown University, 222 Richmond Street, Providence, RI, USA

    Cristina Flores

  11. Department of Medicine, Weill Cornell Medical College, 1300 York Avenue, New York, NY, USA

    Francesca Gany

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  1. Jennifer Leng
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Leng, J., Peruluswami, P., Bari, S. et al. South Asian Health: Inflammation, Infection, Exposure, and the Human Microbiome. J Immigrant Minority Health 21 (Suppl 1), 26–36 (2019). https://doi.org/10.1007/s10903-017-0652-y

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  • DOI: https://doi.org/10.1007/s10903-017-0652-y

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