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A Fluorescent Probe Based on the Hydrazone Schiff Base for the Detection of Zn2+ and its Application on Test Strips

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Abstract

A novel fluorescent probe SHK for Zn2+ detection was designed based on the hydrazone Schiff base, successfully synthesized by Suzuki coupling and condensation reactions. The probe SHK in DMSO/H2O showed extremely weak fluorescence. However, the solution exhibited an intensive yellow-green emission with the introduction of Zn2+. In contrast, negligible fluorescence change was observed when other metal ions were added, suggesting a high selectivity of SHK for Zn2+ detection. The Job’s Plot analysis revealed that a 1:1 stoichiometric adduct SHK-Zn2+ formed during the Zn2+ sensing. The binding constant of the complex was determined to be 184 M− 1, and the detection limit for Zn2+ was calculated to be 112 µM. Moreover, the probe SHK achieved selective fluorescence sensing for Zn2+ on test strips, which guaranteed its practical application prospect.

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No dataset was generated or analyzed during this study.

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Acknowledgements

This work is supported by the Natural Science Foundation of Hainan Province (No. 220RC591) and Students Research Foundation of Hainan Normal University (No. S202211658037).

Funding

Natural Science Foundation of Hainan Province (No. 220RC591) and Students Research Foundation of Hainan Normal University (No. S202211658037).

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Authors and Affiliations

  1. College of Chemistry and Chemical Engineering, Key Laboratory of Water Pollution Treatment & Resource Reuse of Hainan Province, Hainan Normal University, Haikou, 571158, China

    Guo Xu, Shu-Jie Ma, Hua-Hong Zhang, Jing Jing & Xiao-Peng Zhang

  2. College of Chemical Engineering, Nanjing Forestry University, Nanjing, 210037, China

    Xing-Han Chen

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  1. Guo Xu
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Contributions

Guo Xu: Performed the experiments; Analyzed and interpreted the data; Contributed reagents, materials, analysis tools or data; Wrote the paper. Shu-Jie Ma: Performed the experiments; Contributed reagents, materials, analysis tools or data. Hua-Hong Zhang: Performed the experiments; Analyzed and interpreted the data. Jing Jing: Performed the experiments. Xing-Han Chen: Contributed reagents, materials, analysis tools or data. Xiao-Peng Zhang: Conceived and designed the experiments; Analyzed and interpreted the data; Wrote the paper. All authors reviewed the manuscript.

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Correspondence to Xiao-Peng Zhang.

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Xu, G., Ma, SJ., Zhang, HH. et al. A Fluorescent Probe Based on the Hydrazone Schiff Base for the Detection of Zn2+ and its Application on Test Strips. J Fluoresc 33, 1183–1189 (2023). https://doi.org/10.1007/s10895-022-03140-9

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