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A Fluorescent Turn-On Sensor Toward Multiple Heavy Metal Ions Based on Meso-anisole Modified BODIPY Scaffold

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Abstract

A fluorescent turn-on sensor (BOPA) was configured by anchoring bis(pyridin-2-ylmethyl)-amine (DPA) unit to the BODIPY scaffold. It exhibits highly sensitivity and selectivity towards Pb2+, Ba2+, Cr3+, Cd2+, Hg2+, Zn2+ against the competent metal ions. Job’s plot analysis supports the 1:1 stoichiometry of BOPA and metal ions. And linear relationship between fluorescence intensity and concentration of Zn2+ (representative metal ion) was observed over the range 0 ~ 20 μM Zn2+. The limit detection of BOPA in recognition of Pb2+, Ba2+, Cr3+, Cd2+, Hg2+, Zn2+ was ranged from 15.99 to 43.57 nM. Photo induced transfer (PET) in the excited state of BOPA determines the emission “off/on”. Coordination of metal ions by DPA significantly weakened the electron-donating ability of nitrogen atom and inhibits the PET, recovering emission of BODIPY. In addition, the attachment of anisole at meso-position of BODIPY finely modulated the recognition of metal ions category.

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Funding

This work was supported by the National Natural Science Foundation of China (grant no. 21772034) We also thank the financial support from Henan Key Laboratory of Organic Functional Molecules and Drug Innovation.

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Authors and Affiliations

  1. NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan, People’s Republic of China

    Xiaochuan Li & Fangfang Li

  2. Henan Key Laboratory of Medical Polymer Materials Technology and Application, Tuoren Medical Device Research &, Development Institute Co. Ldt, Xinxiang, Henan, People’s Republic of China

    Guangqian Ji

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  1. Xiaochuan Li
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Contributions

All the authors (Guangqian Ji, Fangfang Li, and Xiaochuan Li) made substantial contribution while preparing the manuscript. All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by Guangqian Ji, and Fangfang Li. The first draft of the manuscript was written by Xiaochuan Li. Guangqian Ji prepared Figs. 1–5 and Fangfang Li prepared Scheme 1–3. All authors read and approved the final manuscript.

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Correspondence to Xiaochuan Li.

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Li, X., Li, F. & Ji, G. A Fluorescent Turn-On Sensor Toward Multiple Heavy Metal Ions Based on Meso-anisole Modified BODIPY Scaffold. J Fluoresc 33, 631–637 (2023). https://doi.org/10.1007/s10895-022-03110-1

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