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A Novel Fluorescent Chemosensor for cu (II) Ion: Click Synthesis of Dual-Bodipy Including the Triazole Groups and Bioimaging of Yeast Cells

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Abstract

A fluorescent chemosensor including dual Bodipy units (d-BODIPY) was improved for selective copper (II) sensing in half-aqueous samples. The sensor d-BODIPY has a highly selective and sensitive detection towards Cu (II) over the studied competing for metal cations. The interaction among solutions of Cu (II) and d-BODIPY caused a crucial quenching effect in fluorescence maxima at 548 nm (λex = 470 nm) owing to the electronic trap occurring between the amide and triazole units. The quenching effect without any change in wavelength can be explained by a photoinduced electron transfer (PET) process. The binding constant (Ka) of d-BODIPY with Cu (II) was calculated and also the limit of detection of d-BODIPY for Cu (II) was 1.2 × 10−8 M. In addition, the bio-imaging in the yeast cells suggested that d-BODIPY had an excellent potential to be used to investigate Cu (II).

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Acknowledgments

The authors gratefully thanks to Tübitak (118Z039) for financial support of this work. The authors express their appreciation to Emine Bagci for helpful discussions.

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Authors and Affiliations

  1. Department of Chemistry, University of Selcuk, Campus, 42031, Konya, Turkey

    Ahmed Nuri Kursunlu, Mustafa Ozmen & Ersin Güler

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  1. Ahmed Nuri Kursunlu
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  2. Mustafa Ozmen
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  3. Ersin Güler
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Correspondence to Ahmed Nuri Kursunlu.

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Kursunlu, A.N., Ozmen, M. & Güler, E. A Novel Fluorescent Chemosensor for cu (II) Ion: Click Synthesis of Dual-Bodipy Including the Triazole Groups and Bioimaging of Yeast Cells. J Fluoresc 29, 1321–1329 (2019). https://doi.org/10.1007/s10895-019-02456-3

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  • DOI: https://doi.org/10.1007/s10895-019-02456-3

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