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A Colorimetric Selective Sensing Probe for Calcium Ions with Tunable Dynamic Ranges Using Glutathione Modified Gold Nanoparticles

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Abstract

We have obtained a kind of simple and highly effective method for detection of calcium ions based on glutathione functionalized gold nanoparticles (GSH-GNPs) in this article. The GSH-GNPs can be induced to aggregate immediately in the presence of calcium ions that can be detected by colorimetric response of GNPs monitored by a UV–vis spectrophotometer or even naked eyes, and the detection limit could reach 20 μM. Compared to other metal ions, the GSH-GNPs bound by calcium ions shows higher sensitivity with prominent color changes. Most importantly, the probe not only can be tested the content of calcium ion in the water simply and effectively, but also can be applied to estimate calcium levels in blood with low interference and high sensitivity.

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Authors and Affiliations

  1. College of Food Science and Light Industry, Nanjing Tech University, Nanjing, 211800, Jiangsu, China

    Zhengyu Zhang, Ailin Yuan, Chan Chen, Chunling Zheng & Hong Xu

Authors
  1. Zhengyu Zhang
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  2. Ailin Yuan
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  3. Chan Chen
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  4. Chunling Zheng
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  5. Hong Xu
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Correspondence to Chunling Zheng or Hong Xu.

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Zhang, Z., Yuan, A., Chen, C. et al. A Colorimetric Selective Sensing Probe for Calcium Ions with Tunable Dynamic Ranges Using Glutathione Modified Gold Nanoparticles. J Clust Sci 29, 469–473 (2018). https://doi.org/10.1007/s10876-018-1349-7

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  • DOI: https://doi.org/10.1007/s10876-018-1349-7

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