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Microwave-assisted one-step synthesis of acetate-capped NaYF4:Yb/Er upconversion nanocrystals and their application in bioimaging

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Abstract

Acetate-capped hydrophilic cubic phase NaYF4:Yb/Er upconversion nanophosphors were effectively synthesized in a single step employing a facile microwave-assisted synthesis route by applying relatively low temperatures in a short span of time compared to the conventional synthetic methods. The nanoparticles having a size of about 25 nm exhibit good upconversion luminescence property and can be well dispersed in aqueous solvents as-synthesized. These upconversion nanoparticles were examined for their cytotoxicity and demonstrated to be an effective material for cancer cell imaging using near-infrared radiation.

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Acknowledgement

VK acknowledge the financial support from Department of Science and Technology (DST), India under DST-INSPIRE faculty scheme. KLR is thankful to Ministry of Human Resource Development (MHRD), India, for research fellowship and Center for International Mobility (CIMO), Finland, for doctoral exchange fellowship. NP acknowledges the Doctoral Network for Materials Research at Åbo Akademi University and JMR the Academy of Finland (Projects #260599, 284542) for financial aid. The authors wish to thank Dr. Eudald Casals Mercadal for technical assistance.

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  1. Riikka Arppe

    Present address: Department of Chemistry, University of Copenhagen, 2100, Copenhagen, Denmark

Authors and Affiliations

  1. School of Basic Sciences and Advanced Materials Research Center, Indian Institute of Technology Mandi, Kamand, Mandi, Himachal Pradesh, 175005, India

    Kumbam Lingeshwar Reddy & Venkata Krishnan

  2. Pharmaceutical Sciences Laboratory, Faculty of Sciences and Engineering, Åbo Akademi University, 20520, Turku, Finland

    Neeraj Prabhakar & Jessica M. Rosenholm

  3. Department of Biotechnology, University of Turku, 20014, Turun Yliopisto, Turku, Finland

    Riikka Arppe

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  1. Kumbam Lingeshwar Reddy
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Correspondence to Jessica M. Rosenholm or Venkata Krishnan.

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Reddy, K.L., Prabhakar, N., Arppe, R. et al. Microwave-assisted one-step synthesis of acetate-capped NaYF4:Yb/Er upconversion nanocrystals and their application in bioimaging. J Mater Sci 52, 5738–5750 (2017). https://doi.org/10.1007/s10853-017-0809-z

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