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Encapsulation of hexanal in bio-based cyclodextrin metal organic framework for extended release

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Abstract

Porous materials have been widely studied for encapsulation and controlled release of active species for packaging applications. This study examines the encapsulation efficiency of hexanal in γ-cyclodextrin metal organic frameworks (γ-CDMOF) for potential active packaging applications. γ-CDMOF was synthesized and hexanal was encapsulated in the MOF using a vapor diffusion process. The synthesized MOF was characterized both before and after the encapsulation of hexanal using x-ray diffraction (XRD), scanning electron microscopy (SEM), differential scanning calorimetry (DSC), fourier transform infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA). The diffraction peaks of various planes obtained from XRD characterization matched the theoretically calculated values. We identified the most stable docking sites using energy minimization calculations. FTIR and computational studied indicated hydrogen bonding interactions play a significant role in the stabilization of hexanal and γ-CDMOF inclusion complex. TGA characterization results revealed an encapsulation efficiency of about 15%. DSC and SEM study also supported encapsulation of hexanal in γ-CDMOF.

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Acknowledgements

The authors would like to thank Evan Noel Sommerville, Riley Andrew Harden, & Travis Lang, Cal Poly undergraduates and An-Katrien Pauwels, visiting graduate student, Hasselt University, Belgium for their help with experimental work.

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Authors and Affiliations

  1. Industrial Technology and Packaging, California Polytechnic State University, San Luis Obispo, CA, 93407, USA

    Ajay Kathuria

  2. Materials Engineering, California Polytechnic State University, San Luis Obispo, CA, 93407, USA

    Trevor Harding & Mohsen B. Kivy

  3. School of Packaging, Michigan State University, East Lansing, MI, 48824, USA

    Rafael Auras

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  1. Ajay Kathuria
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  4. Mohsen B. Kivy
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Correspondence to Ajay Kathuria.

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Kathuria, A., Harding, T., Auras, R. et al. Encapsulation of hexanal in bio-based cyclodextrin metal organic framework for extended release. J Incl Phenom Macrocycl Chem 101, 121–130 (2021). https://doi.org/10.1007/s10847-021-01095-1

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  • DOI: https://doi.org/10.1007/s10847-021-01095-1

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