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Localization of pacing and defibrillator leads using standard x-ray views is frequently inaccurate and is not reproducible

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Abstract

Purpose

While the accuracy of roentography for evaluation of lead tip position compared with three-dimensional imaging techniques has been well described, there remains considerable variability in the interpretation of the reproducibility of standard x-ray for right ventricular (RV) and left ventricular (LV) lead position. The aim of this study was to evaluate the accuracy and reliability of right ventricular (RV) and left ventricular (LV) lead tip position as determined by board-certified cardiac electrophysiologists (EP) using standard x-ray views.

Methods

EP interpretations of RV and LV lead tip position using standard x-ray views (posterior-anterior, lateral, and left anterior oblique) were compared to thoracic computed tomography (CT). The accuracy of x-ray interpretation was compared to the reference CT location, and the reproducibility of x-ray interpretation was tested using the free-marginal Kappa statistic.

Results

A total of 58 EPs were invited to participate in the survey with a response rate of 43 % (25/58). The agreement between x-ray and CT lead tip position (accuracy) was 37 % for RV lead, 33 % for longitudinal LV lead, and 41 % for short axis LV lead. Reproducibility was 64 % for RV lead tip (k = 0.46), 58 % for longitudinal LV lead tip (k = 0.37), and 39 % for short axis LV lead tip (k = 0.24).

Conclusions

Conventional roentography is limited in its ability to accurately and reliably determine pacing lead tip position.

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Abbreviations

CRT:

Cardiac resynchronization therapy

PA:

Posterior-anterior

LAO:

Left anterior oblique

RV:

Right ventricle

LV:

Left ventricle

CT:

Computed tomography

References

  1. Burri, H., Domenichini, G., Sunthorn, H., Ganière, V., & Stettler, C. (2012). Comparison of tools and techniques for implanting pacemaker leads on the ventricular mid-septum. Europace, 14(6), 847–852.

    Article  PubMed  Google Scholar 

  2. Teh, A. W., Medi, C., Rosso, R., Lee, G., Gurvitch, R., & Mond, H. G. (2009). Pacing from the right ventricular septum: is there a danger to the coronary arteries? Pacing and Clinical Electrophysiology, 32(7), 894–897.

    Article  PubMed  Google Scholar 

  3. Ng, A. C. T., Allman, C., Vidaic, J., Tie, H., Hopkins, A. P., & Leung, D. Y. (2009). Long-term impact of right ventricular septal versus apical pacing on left ventricular synchrony and function in patients with second- or third-degree heart block. American Journal of Cardiology, 103(8), 1096–1101.

    Article  PubMed  Google Scholar 

  4. Domenichini, G., Sunthorn, H., Fleury, E., Foulkes, H., Stettler, C., & Burri, H. (2012). Pacing of the interventricular septum versus the right ventricular apex: a prospective, randomized study. European Journal of Internal Medicine, 23(7), 621–627.

    Article  PubMed  Google Scholar 

  5. Singh, J. P., Klein, H. U., Huang, D. T., Reek, S., Kuniss, M., Quesada, A., et al. (2011). Left ventricular lead position and clinical outcome in the Multicenter Automatic Defibrillator Implantation Trial–Cardiac Resynchronization Therapy (MADIT-CRT) trial. Circulation, 123(11), 1159–1166.

    Article  PubMed  Google Scholar 

  6. Landis, J. R., & Koch, G. G. (1977). The measurement of observer agreement for categorical data. Biometrics, 33(1), 159–174.

    Article  CAS  PubMed  Google Scholar 

  7. Osmancik, P., Stros, P., Herman, D., Curila, K., Petr, R. (2013) The insufficiency of left anterior oblique and the usefulness of right anterior oblique projection for correct localization of a CT-verified right ventricular lead into the midseptum. Circulation: Arrhythmia and Electrophysiology.

  8. Balt, J. C., van Hemel, N. M., Wellens, H. J. J., & de Voogt, W. G. (2010). Radiological and electrocardiographic characterization of right ventricular outflow tract pacing. Europace, 12(12), 1739–1744.

    Article  PubMed  Google Scholar 

  9. Tse, H.-F., & Lau, C.-P. (1997). Long-term effect of right ventricular pacing on myocardial perfusion and function. Journal of the American College of Cardiology, 29(4), 744–749.

    Article  CAS  PubMed  Google Scholar 

  10. Zhang, X.-H., Chen, H. U. A., Siu, C.-W., Yiu, K.-H., Chan, W.-S., Lee, K. L., et al. (2008). New-onset heart failure after permanent right ventricular apical pacing in patients with acquired high-grade atrioventricular block and normal left ventricular function. Journal of Cardiovascular Electrophysiology, 19(2), 136–141.

    Article  PubMed  Google Scholar 

  11. The, D. T. I. (2002). Dual-chamber pacing or ventricular backup pacing in patients with an implantable defibrillator: the Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial. Journal of the American Medical Association, 288(24), 3115–3123.

    Article  Google Scholar 

  12. Thébault, C., Donal, E., Meunier, C., Gervais, R., Gerritse, B., Gold, M. R., et al. (2012). Sites of left and right ventricular lead implantation and response to cardiac resynchronization therapy observations from the REVERSE trial. European Heart Journal, 33(21), 2662–2671.

    Article  PubMed  Google Scholar 

  13. Khan, F. Z., Salahshouri, P., Duehmke, R., Read, P. A., Pugh, P. J., Elsik, M., et al. (2011). The impact of the right ventricular lead position on response to cardiac resynchronization therapy. Pacing and Clinical Electrophysiology, 34(4), 467–474.

    Article  PubMed  Google Scholar 

  14. Sade, L. E., Demir, O., Atar, I., Muderrisoglu, H., & Ozin, B. (2009). Effect of right ventricular pacing lead on left ventricular dyssynchrony in patients receiving cardiac resynchronization therapy. American Journal of Cardiology, 103(5), 695–700.

    Article  PubMed  Google Scholar 

  15. Rickard, J., Ingelmo, C., Sraow, D., Wilkoff, B. L., Grimm, R. A., Schoenhagen, P., et al. (2011). Chest radiography is a poor predictor of left ventricular lead position in patients undergoing cardiac resynchronization therapy: comparison with multidetector computed tomography. Journal of Interventional Cardiac Electrophysiology, 32(1), 59–65.

    Article  PubMed  Google Scholar 

  16. Duckett, S. G., Ginks, M. R., Knowles, B. R., Ma, Y., Shetty, A., Bostock, J., et al. (2011). Advanced image fusion to overlay coronary sinus anatomy with real-time fluoroscopy to facilitate left ventricular lead implantation in CRT. Pacing and Clinical Electrophysiology, 34(2), 226–234.

    Article  PubMed  Google Scholar 

  17. Blendea, D., Mansour, M., Shah, R. V., Chung, J., Nandigam, V., Heist, E. K., et al. (2007). Usefulness of high-speed rotational coronary venous angiography during cardiac resynchronization therapy. American Journal of Cardiology, 100(10), 1561–1565.

    Article  PubMed  Google Scholar 

  18. Kumar, P., Blendea, D., Nandigam, V., Moore, S. A., Heist, E. K., & Singh, J. P. (2010). Assessment of the post-implant final left ventricular lead position: a comparative study between radiographic and angiographic modalities. Journal of Interventional Cardiac Electrophysiology, 29(1), 17–22.

    Article  PubMed  Google Scholar 

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Acknowledgments

Larry R Jackson II: concept/design, data analysis/interpretation, drafting article, critical revision of article, approval of article

Jonathan P. Piccini Sr.: concept/design, data analysis/interpretation, drafting article, critical revision of article, approval of article

Lynne Hurwitz Koweek: concept/design, data analysis/interpretation, critical revision of article, approval of article

James P. Daubert: concept/design, critical revision of article, approval of article

Brett D. Atwater: concept/design, data analysis/interpretation, drafting article, critical revision of article, approval of article

Ethics

This study is a retrospective analysis of previously collected data. No patient information was obtained for the purposes of this study.

Funding

This work was not supported by any specific funding source.

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Correspondence to Larry R. Jackson II.

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Jackson, L.R., Piccini, J.P., Daubert, J.P. et al. Localization of pacing and defibrillator leads using standard x-ray views is frequently inaccurate and is not reproducible. J Interv Card Electrophysiol 43, 5–12 (2015). https://doi.org/10.1007/s10840-015-9984-5

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  • DOI: https://doi.org/10.1007/s10840-015-9984-5

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