Abstract
Cholesterol is the soft and pulpy fat in our body. This study investigates a novel photonic crystal fiber with a hollow octagonal core configuration for human body cholesterol sensing. The sensor is simulated and modeled based on the finite element method. The proposed sensor model is characterized by various performance parameters, including relative sensitivity, which reveals a value of 92.34% relative sensitivity at the optimum operating frequency of 3.6 THz. The model also exhibits the lowest confinement loss of 3.77 × 10−18 cm−1 at the optimum operating frequency. The proposed cholesterol sensor was modeled using hollow-core photonic crystal fiber (HC-PCF). This HC-PCF has advantages over porous-core PCF, as it provides space for an increased quantity of analytes at the core region.
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Jaszczak, E., Ruman, M., Narkowicz, S., Namieśnik, J., Polkowska, Ż.: Development of an analytical protocol for determination of cyanide in human biological samples based on application of ion chromatography with pulsed amperometric detection. J. Anal. Methods Chem. 2017 (2017)
Wu, J., Wang, L., Wang, Q., Zou, L., Ye, B.: The novel voltammetric method for determination of hesperetin based on a sensitive electrochemical sensor. Talanta 150, 61–70 (2016)
Timofeyenko, Y.G., Rosentreter, J.J., Mayo, S.: Piezoelectric quartz crystal microbalance sensor for trace aqueous cyanide ion determination. Anal. Chem. 79(1), 251–255 (2007)
Buczynski, R.: Photonic crystal fibers. Acta Phys. Polon. Ser. A 106(2), 141–168 (2004)
Issa, N.A., van Eijkelenborg, M.A., Fellew, M., Cox, F., Henry, G., Large, M.C.: Fabrication and study of microstructured optical fibers with elliptical holes. Opt. Lett. 29(12), 1336–1338 (2004)
Pawar, A.Y., Sonawane, D.D., Erande, K.B., Derle, D.V.: Terahertz technology and its applications. Drug Invent. Today 5(2), 157–163 (2013)
Podder, E., Hossain, M.B., Jibon, R.H., Bulbul, A.A.-M., Mondal, H.S.: Chemical sensing through photonic crystal fiber: sulfuric acid detection. Front. Optoelectron. 12(4), 372–381 (2019)
Ademgil, H., Haxha, S.: PCF based sensor with high sensitivity, high birefringence and low confinement losses for liquid analyte sensing applications. Sensors 15(12), 31833–31842 (2015)
Yakasai, I., Abas, P.E., Kaijage, S.F., Caesarendra, W., Begum, F.: Proposal for a quad-elliptical photonic crystal fiber for terahertz wave guidance and sensing chemical warfare liquids. In: Photonics, Vol. 3, p. 78. Multidisciplinary Digital Publishing Institute (2019)
Jepsen, P.U., Møller, U., Merbold, H.: Investigation of aqueous alcohol and sugar solutions with reflection terahertz time-domain spectroscopy. Opt. Express 15(22), 14717–14737 (2007)
Jepsen, P.U., Jensen, J.K., Møller, U.: Characterization of aqueous alcohol solutions in bottles with THz reflection spectroscopy. Opt. Express 16(13), 9318–9331 (2008)
Hasan, M.M., Sen, S., Rana, M.J., Paul, B.K., Habib, M.A., Daiyan, G.M., Ahmed, K.: Heptagonal photonic crystal fiber based chemical sensor in THz regime. In: 2019 joint 8th international conference on informatics, electronics & vision (ICIEV) and 2019 3rd international conference on imaging, vision & pattern recognition (icIVPR), IEEE, pp. 40–44 (2019)
Kanmani, R., Ahmed, K., Roy, S., Ahmed, F., Paul, B.K., Rajan, M.M.: The performance of hosting and core materials for slotted core Q-PCF in terahertz spectrum. Optik 194, 163084 (2019)
Ahmed, K., Ahmed, F., Roy, S., Paul, B.K., Aktar, M.N., Vigneswaran, D., Islam, M.S.: Refractive index-based blood components sensing in terahertz spectrum. IEEE Sens. J. 19(9), 3368–3375 (2019)
Islam, M.S., Sultana, J., Ahmed, K., Islam, M.R., Dinovitser, A., Ng, B.W.-H., Abbott, D.: A novel approach for spectroscopic chemical identification using photonic crystal fiber in the terahertz regime. IEEE Sens. J. 18(2), 575–582 (2017)
Hossain, M.B., Podder, E., Bulbul, A.A.-M., Mondal, H.S.: Bane chemicals detection through photonic crystal fiber in THz regime. Opt. Fiber Technol. 54, 102102 (2020)
Abdullah Al-Mamun, B., Rayhan Habib, J., Sumon Kumar, D., Tonmoy, R., Avijit, S., Hossain, M.B.: PCF based formalin detection by exploring the optical properties in THz regime. Nanosci. Nanotechnology-Asia 10, 1–8 (2020). https://doi.org/10.2174/2210681210999200525171303
Abdullah Al-Mamun, B., HossainRahul, M.B.D., Mahadi, H.: Zeonex-based Tetra-rectangular Core-photonic Crystal Fiber for NaCl Detection. Nanosci. Nanotechnology-Asia 10, 1–9 (2020). https://doi.org/10.2174/2210681210999200708141725
Hossain, M. M., Talukder, M. A.: Optical magnetism in surface plasmon resonance–based sensors for enhanced performance. Plasmonics 1–8 (2020)
Eid, M.M., Rashed, A.N.Z., Bulbul, A.A.-M., Podder, E.: Mono-rectangular core photonic crystal fiber (MRC-PCF) for skin and blood cancer detection. Plasmonics 16, 1–11 (2020)
Shephard, J., MacPherson, W., Maier, R., Jones, J., Hand, D., Mohebbi, M., George, A., Roberts, P., Knight, J.: Single-mode mid-IR guidance in a hollow-core photonic crystal fiber. Opt. Express 13(18), 7139–7144 (2005)
Roberts, P., Couny, F., Sabert, H., Mangan, B., Williams, D., Farr, L., Mason, M., Tomlinson, A., Birks, T., Knight, J.: Ultimate low loss of hollow-core photonic crystal fibres. Opt. Express 13(1), 236–244 (2005)
Pryor, R.W.: Multiphysics modeling using COMSOL®: a first principles approach. Jones & Bartlett Publishers (2009)
Pepper, D.W., Heinrich, J.C.: The finite element method: basic concepts and applications with MATLAB, MAPLE, and COMSOL. CRC Press (2017)
Islam, M.S., Sultana, J., Atai, J., Abbott, D., Rana, S., Islam, M.R.: Ultra low-loss hybrid core porous fiber for broadband applications. Appl. Opt. 56(4), 1232–1237 (2017)
Bulbul, A.A.-M., Imam, F., Awal, M., Mahmud, M.: A novel ultra-low loss rectangle-based porous-core PCF for efficient THz waveguidance: design and numerical analysis. Sensors 20(22), 6500 (2020)
Iqbal, F., Biswas, S., Bulbul, A.A.-M., Rahaman, H., Hossain, B.M., Rahaman, E.M., Awal, A.M.: Alcohol sensing and classification using PCF-based sensor. Sens. Bio-Sens. Res. (2020). https://doi.org/10.1016/j.sbsr.2020.100384
Bulbul, A.A.-M., Rahaman, H., Biswas, S., Hossain, M.B., Nahid, A.-A.: Design and numerical analysis of a PCF-based bio-sensor for breast cancer cell detection in the THz regime. Sens. Bio-Sens. Res. 30, 100388 (2020)
Paul, B.K., Islam, M.S., Ahmed, K., Asaduzzaman, S.: Alcohol sensing over O+ E+ S+ C+ L+ U transmission band based on porous cored octagonal photonic crystal fiber. Photon. Sens. 7(2), 123–130 (2017)
Ghazanfari, A., Li, W., Leu, M.C., Hilmas, G.E.: A novel freeform extrusion fabrication process for producing solid ceramic components with uniform layered radiation drying. Addit. Manuf. 15, 102–112 (2017)
Bise, R.T., Trevor, D.J.: Sol–gel derived microstructured fiber fabrication and characterization. In: Optical fiber communication conference, Optical Society of America (2005)
Cubillas, A.M., Unterkofler, S., Euser, T.G., Etzold, B.J., Jones, A.C., Sadler, P.J., Wasserscheid, P., Russell, P.S.J.: Photonic crystal fibres for chemical sensing and photochemistry. Chem. Soc. Rev. 42(22), 8629–8648 (2013)
Ebendorff-Heidepriem, H., Schuppich, J., Dowler, A., Lima-Marques, L., Monro, T.M.: 3D-printed extrusion dies: a versatile approach to optical material processing. Opt. Mater. Express 4(8), 1494–1504 (2014)
Pysz, D., Kujawa, I., Stępień, R., Klimczak, M., Filipkowski, A., Franczyk, M., Kociszewski, L., Buźniak, J., Haraśny, K., Buczyński, R.: Stack and draw fabrication of soft glass microstructured fiber optics. Bullet. Pol. Acad. Sci. Tech. Sci. 62(4), 667–682 (2014)
Atakaramians, S., Afshar, S., Ebendorff-Heidepriem, H., Nagel, M., Fischer, B.M., Abbott, D., Monro, T.M.: THz porous fibers: design, fabrication and experimental characterization. Opt. Express 17(16), 14053–14062 (2009)
Cruz, A.L., Cordeiro, C., Franco, M.A.: 3D printed hollow-core terahertz fibers. Fibers 6(3), 43 (2018)
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Bulbul, A.AM., Podder, E., Ahammad, S.H. et al. Human body cholesterol detection based on a photonic crystal fiber sensor within a hollow octagonal core configuration. J Comput Electron 22, 1725–1734 (2023). https://doi.org/10.1007/s10825-023-02107-8
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DOI: https://doi.org/10.1007/s10825-023-02107-8