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Multivariate Analysis of the Composition of Pharmaceutical Products Based on Terahertz Time-Domain Spectroscopy

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Journal of Applied Spectroscopy Aims and scope

Multivariate methods were applied to the transmission spectra of pharmaceutical products obtained using the fast Fourier transform of the temporal forms of the terahertz electromagnetic field. By successive application of the principal components and linear discriminant analysis it was possible to classify two drugs, and by independent component analysis it was possible to recover the spectrum of the first component in a mixture of three drugs and identify the characteristic features of the second.

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Correspondence to M. A. Khodasevich.

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Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 88, No. 1, pp. 144–149, January–February, 2021.

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Borisevich, D.A., Goncharenko, A.M., Lyakhnovich, A.V. et al. Multivariate Analysis of the Composition of Pharmaceutical Products Based on Terahertz Time-Domain Spectroscopy. J Appl Spectrosc 88, 132–136 (2021). https://doi.org/10.1007/s10812-021-01151-1

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  • DOI: https://doi.org/10.1007/s10812-021-01151-1

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