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Effect of Model Type on the Accuracy of Polarization and Nephelometric Measurements of Red-Blood-Cell Volume

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Journal of Applied Spectroscopy Aims and scope

The effect of using different mathematical models of a red blood cell on the accuracy of the measured average volume for a population of red blood cells was evaluated. The accuracy was estimated based on regression equations between the retrieved microphysical and measured optical properties. Models of a sphere, oblate spheroid, and biconcave discoid represented as a disc with rounded edges and concavities in the middle were analyzed. It was shown that the error of the regression equations when determining the average red-blood-cell volume using the biconcave discoid model was 1%; spheroid, ~8%; and sphere, ~21%. The error of the average volume due to the model is a few percent for the spheroid and ~20% for the sphere.

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Authors and Affiliations

  1. Belarusian State University, 4 Nezavisimost′ Ave., Minsk, 220030, Belarus

    M. M. Kugeiko & D. A. Smunev

Authors
  1. M. M. Kugeiko
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  2. D. A. Smunev
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Correspondence to M. M. Kugeiko.

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Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 83, No. 2, pp. 222–229, March–April, 2016.

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Kugeiko, M.M., Smunev, D.A. Effect of Model Type on the Accuracy of Polarization and Nephelometric Measurements of Red-Blood-Cell Volume. J Appl Spectrosc 83, 204–211 (2016). https://doi.org/10.1007/s10812-016-0270-9

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  • DOI: https://doi.org/10.1007/s10812-016-0270-9

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