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The potential of fucoidans from Chnoospora minima and Sargassum polycystum in cosmetics: antioxidant, anti-inflammatory, skin-whitening, and antiwrinkle activities

  • 8th Asian Pacific Phycological Forum
  • Published:
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Abstract

Over the years, bioactive and biocompatible natural products have received increased attention as ingredients of cosmeceutical formulations owing to their robust properties compared to many of the synthetic chemicals in use. Many natural products derived from algae have shown promising cosmetizing properties. Seaweed polysaccharides, in particular, have received increased attention for their biofunctional and physicochemical characteristics. This study aimed to design a cost-effective strategy to purify fucoidans from the untapped brown algae Chnoospora minima (CMF) and Sargassum polycystum (SPF) harvested in Sri Lanka and to evaluate their cosmetizing properties. Based on Fourier transform infrared (FTIR) spectroscopy and monosaccharide composition analysis, the purified polysaccharides were rich in fucoidan. Relatively high sulfate content was detected in both fucoidans. Experiments were carried out to evaluate antioxidant, UV-protective, anti-inflammatory, antiwrinkling, and skin-whitening effects. Both CMF and SPF showed 2,2-diphenyl-1-picrylhydrazyl (DPPH) and alkyl radical-scavenging activities, anti-inflammatory effects on lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages, considerable collagenase and elastase inhibitory properties and skin-whitening effects via direct inhibition of tyrosinase, and intracellular melanin synthesis indicating promising cosmetizing effects.

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Acknowledgements

This research was supported by a grant from the Marine Biotechnology Program (20170488) funded by the Ministry of Oceans and Fisheries, Korea.

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Authors and Affiliations

  1. Department of Marine Life Science, Jeju National University, Jeju, 690-756, Republic of Korea

    I. P. Shanura Fernando, K. K. Asanka Sanjeewa, Hyun-Soo Kim, Won Woo Lee & You-Jin Jeon

  2. Industrial Technology Institute (ITI), 363, Bauddhaloka Mawatha, Colombo 7, Sri Lanka

    Kalpa W. Samarakoon & U. K. D. S. S. Gunasekara

  3. Department of Family Medicine College of Medicine, Dong-A University, Dong-A University Medical Center, Busan, 602-715, South Korea

    Young-Jin Park

  4. Department of Chemistry, University of Colombo, Colombo 3, Sri Lanka

    D. T. U. Abeytunga

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  1. I. P. Shanura Fernando
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  2. K. K. Asanka Sanjeewa
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  3. Kalpa W. Samarakoon
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  4. Hyun-Soo Kim
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  5. U. K. D. S. S. Gunasekara
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  6. Young-Jin Park
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  7. D. T. U. Abeytunga
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  8. Won Woo Lee
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  9. You-Jin Jeon
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Correspondence to Won Woo Lee or You-Jin Jeon.

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Shanura Fernando, I.P., Asanka Sanjeewa, K.K., Samarakoon, K.W. et al. The potential of fucoidans from Chnoospora minima and Sargassum polycystum in cosmetics: antioxidant, anti-inflammatory, skin-whitening, and antiwrinkle activities. J Appl Phycol 30, 3223–3232 (2018). https://doi.org/10.1007/s10811-018-1415-4

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  • DOI: https://doi.org/10.1007/s10811-018-1415-4

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