Abstract
Purpose
We intended to review the clinical features and histological findings of eyelid lesions in Sri Lanka.
Methods
We conducted a descriptive cross-sectional study to analyse clinicopathological characteristics of eyelid lesions from 2013 to 2017 in the National Eye Hospital of Sri Lanka.
Results
The age of patients ranged from 3 months to 83 years (mean = 46 ± 21 years). The male-to-female ratio in the sample was 1:1.3. Among 654 histologically confirmed eyelid lesions, the majority (n = 407/654, 62%) were neoplastic lesions including 322 benign, 11 premalignant and 74 malignant neoplasms. The commonest benign tumour was seborrheic keratosis (n = 98), and the commonest non-neoplastic lesion was pyogenic granuloma (n = 64). Seventy-four patients had malignant neoplasia including 24 sebaceous carcinoma, 18 basal cell carcinoma, and 14 squamous cell carcinoma. The most common site of malignant lesions was the upper eyelid. The mean age of patients with malignant eyelid lesions was 64 ± 13 years.
Conclusions
Neoplastic lesions outnumbered nonneoplastic lesions, while benign neoplasia was more common than malignant neoplasia. In contrast to the western reports, the commonest malignant neoplasm was sebaceous carcinoma.
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Acknowledgements
We would like to thank Dr. K.S Liyanage, Dr. M.Y.K Wilfred, Dr. A.S.B de Silva, Dr. I.L.M Riffaz and Dr. N.L.S.N Fernando, the Directors of the National Eye Hospital, for administrative support. The authors also thank the laboratory staff of the National Eye Hospital, Mrs. Ruvini Padmasiri, Mr. Saranath Cooray and Mr. Mahesh, for the technical support.
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DP, MM and YM contributed to the study conception and design. Material preparation, data collection and analysis were performed by MP, DK and DP. The first draft of the manuscript was written by YM and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
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This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Review Committee of the National Eye Hospital Sri Lanka.
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Nanayakkara, D.P.S., Dissanayake, M.M., Gunaratne, M.P. et al. Clinicopathological analysis of eyelid lesions in Sri Lanka. Int Ophthalmol 43, 2513–2519 (2023). https://doi.org/10.1007/s10792-023-02651-z
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DOI: https://doi.org/10.1007/s10792-023-02651-z