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The role of simple inflammatory blood parameters in idiopathic epiretinal membrane patients

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Abstract

Aim

To evaluate the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in idiopathic epiretinal membrane (IERM) patients, and their relations with visual acuity.

Method

Fifty-seven IERM and 51 control patients were included. All patients underwent comprehensive ophthalmological examination and complete blood count tests, and NLR and PLR values were calculated. Patients with IERM were compared with the control group, and associations with visual prognosis were evaluated. These ratios’ cut-off values for IERM were also calculated

Results

NLR values were statistically significantly higher in the IERM group than in the control group (p = 0.001). No significant difference was observed between the IERM and control groups in terms of PLR (p = 0.43). No significant correlation was determined between visual acuity and NLR or PLR (r = 0.05, p = 0.66; and r = 0.18, p = 0.16, respectively). The cut-off value for NLR was 1.91.

Conclusion

Patients with IERM showed significantly increased NLR compared to control subjects suggesting that IERM patients may be prone to have high NLR values.

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Acknowledgements

Approval of the Institutional Review Board (IRB). The study was approved by Karadeniz Technical University, Faculty of Medicine.

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Authors and Affiliations

  1. Department of Ophthalmology, Medical Faculty, Karadeniz Technical University, Trabzon, Turkey

    Dilek Uzlu, Hidayet Erdöl, Ahmet Mehmet Somuncu, Ahmet Duhan Özbay & Mehmet Kola

  2. The State Hospital of Bayburt, Bayburt, Turkey

    Büşra Köse

Authors
  1. Dilek Uzlu
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  2. Hidayet Erdöl
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  3. Ahmet Mehmet Somuncu
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  4. Ahmet Duhan Özbay
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  5. Mehmet Kola
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  6. Büşra Köse
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Correspondence to Dilek Uzlu.

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The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article. There is no funding statement.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by Karadeniz Technical University, Faculty of Medicine, Ethic Council on 2019/268.

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Informed consent was obtained from all individual participants included in the study.

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Uzlu, D., Erdöl, H., Somuncu, A.M. et al. The role of simple inflammatory blood parameters in idiopathic epiretinal membrane patients. Int Ophthalmol 41, 107–112 (2021). https://doi.org/10.1007/s10792-020-01557-4

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  • DOI: https://doi.org/10.1007/s10792-020-01557-4

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