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An objective evaluation of crystalline lens density using Scheimpflug lens densitometry in different uveitis entities

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Abstract

Aim

To measure lens densities with a Pentacam HR device in patients with active uveitis. Measurements were taken at the onset of the attack and after the treatment of inflammation.

Methods

The study included 51 eyes with different anterior uveitis aetiologies and a control group of 48 eyes of age- and gender-matched healthy subjects. Lens densitometry measurements were taken with a Scheimpflug camera on a Pentacam HR device. All the examinations and measurements were performed on the first presentation with the onset of the attack and were repeated at 1st and 3rd months after treatment. Lens densitometry measurements were compared with those of the healthy control group and the healthy fellow eyes of the uveitic patients.

Results

No statistically significant difference was determined between the groups in respect of age and gender (p > 0.05). At 3 months, Pentacam densitometry of zones 3 value was determined to be significantly high in the uveitic eyes compared to the healthy eyes (p = 0.018). The average lens density value (ALD) at 1 month was statistically significantly higher than the baseline value in the uveitic eyes (p = 0.034). There was no significant change in the ALD value at 3 months compared to the baseline and 1-month values (p = 0.386, p = 0.736, respectively).

Conclusion

Even if there is no cataract development that can be clinically observed in eyes with anterior uveitis, lens density in zone 3 showed a significant increase at the end of 3 months compared to the baseline value. This change can be evaluated objectively with Scheimpflug imaging.

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Funding

The authors have no proprietary or commercial interest in any materials discussed in this article.

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Authors and Affiliations

  1. Ulucanlar Eye Training and Research Hospital, Ankara, Turkey

    Gözde Bayrak & Burcu Kazanci

  2. Department of Ophthalmology, University of Health Sciences, Ulucanlar Eye Training and Research Hospital, Ankara, 06240, Turkey

    Yasemin Özdamar Erol

Authors
  1. Gözde Bayrak
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  2. Yasemin Özdamar Erol
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  3. Burcu Kazanci
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Correspondence to Yasemin Özdamar Erol.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Bayrak, G., Özdamar Erol, Y. & Kazanci, B. An objective evaluation of crystalline lens density using Scheimpflug lens densitometry in different uveitis entities. Int Ophthalmol 40, 2031–2040 (2020). https://doi.org/10.1007/s10792-020-01379-4

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  • DOI: https://doi.org/10.1007/s10792-020-01379-4

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