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The Effect of Pressure-Controlled Ventilation and Volume-Controlled Ventilation in Prone Position on Pulmonary Mechanics and Inflammatory Markers

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ABSTRACT

The aim of this present study is to compare the effect of pressure-controlled ventilation and volume-controlled ventilation on pulmonary mechanics and inflammatory markers in prone position. The study included 41 patients undergoing to vertebrae surgery. The patients were randomized into two groups: Group 1 received volume-controlled ventilation, while group 2 received pressure-controlled ventilation. The demographic data, pulmonary mechanics, the inflammatory marker levels just after the induction of anesthetics, at the 6th and 12th hours, and gas analysis from arterial blood samples taken at the beginning and the 30th minute were recorded. The inflammatory marker levels increased in both groups, without any significant difference among groups. Peak inspiratory pressure level was higher in the volume-controlled ventilation group. This study revealed that there is no difference regarding inflammatory marker levels between volume- and pressure-controlled ventilation.

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Authors and Affiliations

  1. Medical Faculty Department of Anesthesia and Reanimation, Afyon Kocatepe University, Afyonkarahisar, Turkey

    Hasan Şenay, Remziye Sıvacı, Serdar Kokulu, Elif Doğan Bakı & Yüksel Ela

  2. Tıp Fakültesi, Anesteziyoloji ve Reanimasyon AD, Kocatepe Üniversitesi, İzmir Yolu 8. Km, Afyonkarahisar, Turkey

    Remziye Sıvacı

  3. Medical Faculty Department of Medical Biochemistry, Afyon Kocatepe University, Afyonkarahisar, Turkey

    Buğra Koca

Authors
  1. Hasan Şenay
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  2. Remziye Sıvacı
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  3. Serdar Kokulu
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  4. Buğra Koca
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  5. Elif Doğan Bakı
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  6. Yüksel Ela
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Correspondence to Remziye Sıvacı.

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Approval was obtained from the local Ethics Board of Afyon Kocatepe University Facullty of Medicine.

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Şenay, H., Sıvacı, R., Kokulu, S. et al. The Effect of Pressure-Controlled Ventilation and Volume-Controlled Ventilation in Prone Position on Pulmonary Mechanics and Inflammatory Markers. Inflammation 39, 1469–1474 (2016). https://doi.org/10.1007/s10753-016-0379-2

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  • DOI: https://doi.org/10.1007/s10753-016-0379-2

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