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The use of antioxidative stress enzymes, lipid peroxidation, and red blood cell abnormalities as biomarkers of stress in Periphthalmus papilio of the polluted coastal Lagos lagoon

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Abstract

We assessed the mudskipper, Periphthalmus papilio inhabiting the coast line of the Lagos lagoon, Gulf of Guinea, to determine suitable biomarkers of stress due to its current status as a polluted water body. The gill and liver samples showed evidence of some activities of antioxidative stress enzymes including catalase, superoxide dismutase, glutathione-s-transferase, reduced glutahthione, as well as some detectable levels of lipid peroxidation product. The stress status of the fishes was also elucidated by nuclear abnormalities especially micronucleus formation and the presence of numerous vacuolated red blood cells. Given the current need for more sensitive bioindicators in monitoring pollution in this lagoon, we hereby present these inherent responses in P. papilio as a suitable candidate for incorporation into the current repertoire for ecotoxicological investigations in polluted water bodies of the Gulf of Guinea coastline.

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Acknowledgments

The authors acknowledge the help of veteran ecologist now deceased, Mr E.A. Faton formerly of the Department of Zoology, University of Lagos for his assistance in the collection of mudskippers from the Lagoon.

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Authors and Affiliations

  1. Ecotoxicology and Conservation Unit, Ecotoxicology Laboratory, Department of Zoology, University of Lagos, Akoka-Yaba, Lagos, Nigeria

    Amaeze H. Nnamdi, Adepegba E. Adeladun, Kolapo Oyenike & Egonmwan I. Rosemary

  2. Molecular and Cell Culture Laboratory, Department of Cell Biology and Genetics, University of Lagos, Akoka-Yaba, Lagos, Nigeria

    Adebesin A. Olumide

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  1. Amaeze H. Nnamdi
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Correspondence to Amaeze H. Nnamdi.

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Nnamdi, A.H., Olumide, A.A., Adeladun, A.E. et al. The use of antioxidative stress enzymes, lipid peroxidation, and red blood cell abnormalities as biomarkers of stress in Periphthalmus papilio of the polluted coastal Lagos lagoon. Environ Monit Assess 187, 103 (2015). https://doi.org/10.1007/s10661-015-4331-y

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