Abstract
Despite the substantial evidence that supports the efficacy of cognitive-behavioral therapy for the treatment of anxiety and related disorders, our understanding of mechanisms of change throughout treatment remains limited. The goal of the current study was to examine changes in experiential avoidance across treatment in a sample of participants (N = 179) with heterogeneous anxiety disorders receiving various cognitive-behavioral therapy protocols. Univariate latent growth curve models were conducted to examine change in experiential avoidance across treatment, followed by parallel process latent growth curve models to examine the relationship between change in experiential avoidance and change in anxiety symptoms. Finally, bivariate latent difference score models were conducted to examine the temporal precedence of change in experiential avoidance and change in anxiety. Results indicated that there were significant reductions in experiential avoidance across cognitive-behavioral treatment, and that change in experiential avoidance was significantly associated with change in anxiety. Results from the latent difference score models indicated that change in experiential avoidance preceded and predicted subsequent changes in anxiety, whereas change in anxiety did not precede and predict subsequent changes in experiential avoidance. Taken together, these results provide additional support for reductions in experiential avoidance as a transdiagnostic mechanism in cognitive-behavioral therapy.
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Notes
Number of treatment sessions in the Unified Protocol condition were based on the recommended number of sessions in each SDP to control for number of sessions across active treatment conditions.
Additional univariate LGMs examined reductions in EA (MEAQ total score and MEAQ-DA subscale) within the Unified Protocol and Single Disorder Protocol conditions separately, and indicated that there were significant reductions in EA (MEAQ total score and MEAQ-DA) within each treatment condition, and no significant differences between the Unified Protocol and Single Disorder Protocol conditions.
References
Akbari, M., & Khanipour, H. (2018). The transdiagnostic model of worry: The mediating role of experiential avoidance. Personality and Individual Differences,135, 166–172. https://doi.org/10.1016/j.paid.2018.07.011.
Arch, J. J., & Craske, M. G. (2008). Acceptance and commitment therapy and cognitive behavioral therapy for anxiety disorders: Different treatments, similar mechanisms? Clinical Psychology: Science and Practice,15(4), 263–279. https://doi.org/10.1111/j.1468-2850.2008.00137.x.
Arch, J. J., Wolitzky-Taylor, K. B., Eifert, G. H., & Craske, M. G. (2012). Longitudinal treatment mediation of traditional cognitive behavioral therapy and acceptance and commitment therapy for anxiety disorders. Behaviour Research and Therapy,50(7–8), 469–478. https://doi.org/10.1016/j.brat.2012.04.007.
Barlow, D. H., Allen, L. B., & Choate, M. L. (2004). Toward a unified treatment for emotional disorders. Behavior Therapy,35(2), 205–230. https://doi.org/10.1016/S0005-7894(04)80036-4.
Barlow, D. H., & Craske, M. G. (2006). Mastery of your anxiety and panic (4th ed.). Oxford: Oxford University Press.
Barlow, D. H., Farchione, T. J., Bullis, J. R., Gallagher, M. W., Murray-Latin, H., Sauer-Zavala, S., et al. (2017). The unified protocol for transdiagnostic treatment of emotional disorders compared with diagnosis-specific protocols for anxiety disorders: A randomized clinical trial. JAMA Psychiatry,74(9), 875. https://doi.org/10.1001/jamapsychiatry.2017.2164.
Barlow, D. H., Farchione, T. J., Sauer-Zavala, S., Latin, H. M., Ellard, K. K., Bullis, J. R., et al. (2018). Unified protocol for transdiagnostic treatment of emotional disorders: Workbook (2nd ed.). New York: Oxford University Press.
Bentler, P. M. (1990). Comparative fit indexes in structural models. Psychological Bulletin,107(2), 238–246. https://doi.org/10.1037/0033-2909.107.2.238.
Blalock, J. A., & Joiner, T. E. (2000). Interaction of cognitive avoidance coping and stress in predicting depression/anxiety. Cognitive Therapy and Research,24(1), 47–65. https://doi.org/10.1023/A:1005450908245.
Bond, F. W., Hayes, S. C., Baer, R. A., Carpenter, K. M., Guenole, N., Orcutt, H. K., et al. (2011). Preliminary psychometric properties of the acceptance and action questionnaire-II: A revised measure of psychological inflexibility and experiential avoidance. Behavior Therapy,42(4), 676–688. https://doi.org/10.1016/j.beth.2011.03.007.
Boswell, J. F., Anderson, L. M., & Barlow, D. H. (2014). An idiographic analysis of change processes in the unified transdiagnostic treatment of depression. Journal of Consulting and Clinical Psychology,82(6), 1060–1071. https://doi.org/10.1037/a0037403.
Brown, T. A., & Barlow, D. H. (2014). Anxiety and related disorders interview schedule for DSM-5 (ADIS-5) - adult version: Client interview schedule 5-copy set. Oxford: Oxford University Press.
Brown, T. A., DiNardo, P., & Barlow, D. H. (1994). Anxiety disorders interview schedule adult version (ADIS-IV): Client interview schedules. Oxford: Oxford University Press.
Butler, A. C., Chapman, J. E., Forman, E. M., & Beck, A. T. (2006). The empirical status of cognitive-behavioral therapy: A review of meta-analyses. Clinical Psychology Review,26(1), 17–31. https://doi.org/10.1016/j.cpr.2005.07.003.
Chawla, N., & Ostafin, B. (2007). Experiential avoidance as a functional dimensional approach to psychopathology: An empirical review. Journal of Clinical Psychology,63(9), 871–890. https://doi.org/10.1002/jclp.20400.
Ciarrochi, J., Bilich, L., & Godsell, C. (2010). Psychological flexibility as a mechanism of change in acceptance and commitment therapy. Assessing mindfulness and acceptance processes in clients: Illuminating the theory and practice of change (pp. 51–75). Oakland, CA: Context Press/New Harbinger Publications.
Craske, M. G., & Barlow, D. H. (2007). Mastery of your anxiety and panic: Therapist guide. Oxford: Oxford University Press.
Dalrymple, K. L., & Herbert, J. D. (2007). Acceptance and commitment therapy for generalized social anxiety disorder: A pilot study. Behavior Modification,31(5), 543–568. https://doi.org/10.1177/0145445507302037.
Espejo, E. P., Gorlick, A., & Castriotta, N. (2017). Changes in threat-related cognitions and experiential avoidance in group-based transdiagnostic CBT for anxiety disorders. Journal of Anxiety Disorders,46, 65–71. https://doi.org/10.1016/j.janxdis.2016.06.006.
Eustis, E. H., Hayes-Skelton, S. A., Roemer, L., & Orsillo, S. M. (2016). Reductions in experiential avoidance as a mediator of change in symptom outcome and quality of life in acceptance-based behavior therapy and applied relaxation for generalized anxiety disorder. Behaviour Research and Therapy,87, 188–195. https://doi.org/10.1016/j.brat.2016.09.012.
Farchione, T. J., Fairholme, C. P., Ellard, K. K., Boisseau, C. L., Thompson-Hollands, J., Carl, J. R., et al. (2012). Unified protocol for transdiagnostic treatment of emotional disorders: A randomized controlled trial. Behavior Therapy,43(3), 666–678. https://doi.org/10.1016/j.beth.2012.01.001.
Ferrer, E., & McArdle, J. (2003). Alternative structural models for multivariate longitudinal data analysis. Structural Equation Modeling,10(4), 493–524. https://doi.org/10.1207/S15328007SEM1004_1.
Foa, E. B., Yadin, E., & Lichner, T. K. (2012a). Exposure and response (ritual) prevention for obsessive compulsive disorder: Therapist guide (2nd ed.). Oxford: Oxford University Press.
Foa, E. B., Yadin, E., & Lichner, T. K. (2012b). Treating your OCD with exposure and response (ritual) prevention: Workbook (2nd ed.). New York: Oxford University Press.
Gallagher, M. W., Sauer-Zavala, S. E., Boswell, J. F., Carl, J. R., Bullis, J., Farchione, T. J., et al. (2013). The impact of the unified protocol for emotional disorders on quality of life. International Journal of Cognitive Therapy,6(1), 57–72. https://doi.org/10.1521/ijct.2013.6.1.57.
Gámez, W., Chmielewski, M., Kotov, R., Ruggero, C., & Watson, D. (2011). Development of a measure of experiential avoidance: The multidimensional experiential avoidance questionnaire. Psychological Assessment,23(3), 692–713. https://doi.org/10.1037/a0023242.
Hamilton, M. (1959). The assessment of anxiety states by rating. British Journal of Medical Psychology,32(1), 50–55. https://doi.org/10.1111/j.2044-8341.1959.tb00467.x.
Hayes, S. C., Bissett, R. T., Korn, Z., Zettle, R. D., Rosenfarb, I. S., Cooper, L. D., et al. (1999). The impact of acceptance versus control rationales on pain tolerance. The Psychological Record,49(1), 33–47. https://doi.org/10.1007/BF03395305.
Hayes, S. C., Pistorello, J., & Levin, M. E. (2012). Acceptance and commitment therapy as a unified model of behavior change. The Counseling Psychologist,40(7), 976–1002. https://doi.org/10.1177/0011000012460836.
Hayes, S. C., Strosahl, K. D., & Wilson, K. G. (2011). Acceptance and commitment therapy, second edition: The process and practice of mindful change (2nd ed.). New York: Guilford Press.
Hayes, S. C., Strosahl, K., Wilson, K. G., Bissett, R. T., Pistorello, J., Toarmino, D., et al. (2004). Measuring experiential avoidance: A preliminary test of a working model. The Psychological Record,54(4), 553–578. https://doi.org/10.1007/BF03395492.
Hayes, S. C., Wilson, K. G., Gifford, E. V., Follette, V. M., & Strosahl, K. (1996). Experiential avoidance and behavioral disorders: A functional dimensional approach to diagnosis and treatment. Journal of Consulting and Clinical Psychology,64(6), 1152–1168. https://doi.org/10.1037/0022-006X.64.6.1152.
Hayes-Skelton, S. A., Usmani, A., Lee, J. K., Roemer, L., & Orsillo, S. M. (2012). A fresh look at potential mechanisms of change in applied relaxation for generalized anxiety disorder: A case series. Cognitive and Behavioral Practice,19(3), 451–462. https://doi.org/10.1016/j.cbpra.2011.12.005.
Hofmann, S. G., & Smits, J. A. J. (2008). Cognitive-behavioral therapy for adult anxiety disorders: A meta-analysis of randomized placebo-controlled trials. The Journal of Clinical Psychiatry,69(4), 621–632. https://doi.org/10.4088/jcp.v69n0415.
Hope, D. A., Heimberg, R. G., & Turk, C. L. (2006). Managing social anxiety: A cognitive-behavioral therapy approach: Therapist guide (1st ed.). Oxford: Oxford University Press.
Hope, D. A., Heimberg, R. G., & Turk, C. L. (2010). Managing social anxiety: A cognitive-behavioral therapy approach (2nd ed.). New York: Oxford University Press.
Kazdin, A. E. (2007). Mediators and mechanisms of change in psychotherapy research. Annual Review of Clinical Psychology,3(1), 1–27. https://doi.org/10.1146/annurev.clinpsy.3.022806.091432.
Kocovski, N. L., Fleming, J. E., Hawley, L. L., Ho, M.-H. R., & Antony, M. M. (2015). Mindfulness and acceptance-based group therapy and traditional cognitive behavioral group therapy for social anxiety disorder: Mechanisms of change. Behaviour Research and Therapy,70, 11–22. https://doi.org/10.1016/j.brat.2015.04.005.
Kocovski, N. L., Fleming, J. E., & Rector, N. A. (2009). Mindfulness and acceptance-based group therapy for social anxiety disorder: An open trial. Cognitive and Behavioral Practice,16(3), 276–289. https://doi.org/10.1016/j.cbpra.2008.12.004.
McArdle, J. J., & Nesselroade, J. R. (1994). Using multivariate data to structure developmental change. In The West Virginia University Conferences on Life-Span Developmental Psychology. Life-span developmental psychology: Methodological contributions (pp. 223–267). Hillsdale, NJ: Lawrence Erlbaum Associates, Inc.
Meyer, E. C., Kotte, A., Kimbrel, N. A., DeBeer, B. B., Elliott, T. R., Gulliver, S. B., et al. (2019). Predictors of lower-than-expected posttraumatic symptom severity in war veterans: The influence of personality, self-reported trait resilience, and psychological flexibility. Behaviour Research and Therapy,113, 1–8. https://doi.org/10.1016/j.brat.2018.12.005.
Muthén, L. K., & Muthén, B. O. (1998). Mplus user’s guide: Statistical analysis with latent variables (7th ed.). Los Angeles, CA: Muthén & Muthén.
Naragon-Gainey, K., & Watson, D. (2018). What lies beyond neuroticism? An examination of the unique contributions of social-cognitive vulnerabilities to internalizing disorders. Assessment,25(2), 143–158. https://doi.org/10.1177/1073191116659741.
Orcutt, H. K., Pickett, S. M., & Pope, B. E. (2005). Experiential avoidance and forgiveness as mediators in the relation between traumatic interpersonal events and posttraumatic stress disorder symptoms. Journal of Social and Clinical Psychology,24(7), 1003–1029. https://doi.org/10.1521/jscp.2005.24.7.1003.
Rochefort, C., Baldwin, A. S., & Chmielewski, M. (2018). Experiential avoidance: An examination of the construct validity of the AAQ-II and MEAQ. Behavior Therapy,49(3), 435–449. https://doi.org/10.1016/j.beth.2017.08.008.
Roemer, L., & Borkovec, T. D. (1994). Effects of suppressing thoughts about emotional material. Journal of Abnormal Psychology,103(3), 467–474. https://doi.org/10.1037/0021-843X.103.3.467.
Roemer, L., & Orsillo, S. M. (2009). Mindfulness- and acceptance-based behavioral therapies in practice. New York: The Guilford Press.
Roemer, L., & Orsillo, S. M. (2014). An acceptance-based behavioral therapy for generalized anxiety disorder. In Clinical handbook of psychological disorders, fifth edition: A step-by-step treatment manual (5th ed., pp. 206–236). New York: The Guilford Press.
Roemer, L., Orsillo, S. M., & Salters-Pedneault, K. (2008). Efficacy of an acceptance-based behavior therapy for generalized anxiety disorder: Evaluation in a randomized controlled trial. Journal of Consulting and Clinical Psychology,76(6), 1083–1089. https://doi.org/10.1037/a0012720.
Shear, M. K., Vander Bilt, J., Rucci, P., Endicott, J., Lydiard, B., Otto, M. W., et al. (2001). Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depression and Anxiety,13(4), 166–178. https://doi.org/10.1002/da.1033.
Spinhoven, P., van Hemert, A. M., & Penninx, B. W. J. H. (2017). Experiential avoidance and bordering psychological constructs as predictors of the onset, relapse and maintenance of anxiety disorders: One or many? Cognitive Therapy and Research,41(6), 867–880. https://doi.org/10.1007/s10608-017-9856-7.
Steiger, J. H. (1990). Structural model evaluation and modification: An interval estimation approach. Multivariate Behavioral Research,25(2), 173–180. https://doi.org/10.1207/s15327906mbr2502_4.
Tucker, L. R., & Lewis, C. (1973). A reliability coefficient for maximum likelihood factor analysis. Psychometrika,38(1), 1–10. https://doi.org/10.1007/BF02291170.
Wegner, D. M., Schneider, D. J., Carter, S. R., & White, T. L. (1987). Paradoxical effects of thought suppression. Journal of Personality and Social Psychology,53(1), 5–13. https://doi.org/10.1037//0022-3514.53.1.5.
Wolgast, M. (2014). What does the acceptance and action questionnaire (AAQ-II) really measure? Behavior Therapy,45(6), 831–839. https://doi.org/10.1016/j.beth.2014.07.002.
Zinbarg, R. E., Craske, M. G., & Barlow, D. H. (2006). Mastery of your anxiety and worry (2nd ed.). Oxford: Oxford University Press.
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The authors thank Sarah A. Hayes-Skelton for her statistical consultation.
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This work was supported by National Institute of Mental Health Grant No. MH090053 awarded to the last author.
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Dr. Barlow receives royalties from Oxford University Press (which includes royalties for all five treatment manuals included in this study), Guilford Publications Inc., Cengage Learning, and Pearson Publishing. Grant monies for various projects including this one come from the National Institute of Mental Health, the National Institute of Alcohol and Alcohol Abuse, and Colciencias (Government of Columbia Initiative for Science, Technology, and Health Innovation). Consulting and honoraria during the past several years have come from the Agency for Healthcare Research and Quality, the Foundation for Informed Medical Decision Making, the Department of Defense, the Renfrew Center, the Chinese University of Hong Kong, Universidad Católica de Santa Maria (Arequipa, Peru), New Zealand Psychological Association, Hebrew University of Jerusalem, Mayo Clinic, and various American Universities and Institutes. Drs. Farchione and Sauer-Zavala receive royalties from Oxford University Press (for one of the treatment manuals included in this study). The other authors do not have any disclosures to report.
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Eustis, E.H., Cardona, N., Nauphal, M. et al. Experiential Avoidance as a Mechanism of Change Across Cognitive-Behavioral Therapy in a Sample of Participants with Heterogeneous Anxiety Disorders. Cogn Ther Res 44, 275–286 (2020). https://doi.org/10.1007/s10608-019-10063-6
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DOI: https://doi.org/10.1007/s10608-019-10063-6