The new natural saponin 3β,16α-dihydroxy-23-oxo-oleanan-28,13β-olide (1) was isolated from the aerial part of Saponaria officinalis. Its structure was established by analyzing 1D and 2D NMR spectroscopic and high-resolution mass-spectrometric data. The antimicrobial activity of the new saponin against the microorganisms Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Bacillus subtilis, and Candida albicans was studied.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
A. Dashti, Iran. J. Bot., 2, 24 (2018).
V. Y. Chirva, P. K. Kintya, and G. V. Lazur′evskii, Chem. Nat. Compd., 5, 52 (1969).
K. Koike, Z. Jia, and T. Nikaido, J. Nat. Prod., 62, 1655 (1999).
Z. Jia, K. Koike, and T. Nikaido, J. Nat. Prod., 61, 1368 (1998).
Z. Jia, K. Koike, and T. Nikaido, J. Nat. Prod., 62, 449 (1999).
W. Smulek, A. Zdarta, A. Pacholak, A. Zgola-Grzeskowiak, L. Marczak, M. Jarzebski, and E. Kaczorek, Colloids Surf., B, 150, 209 (2017).
Plant Resources of the USSR: Flowering Plants, Their Chemical Composition and Use. Families Caprifoliaceae–Plantaginaceae, Nauka, Moscow, 1990, p. 328.
G. B. Endonova, T. P. Antsupova, and S. D. Zhamsaranova, Khim. Rastit. Syr′ya, No. 1, 137 (2018).
M. Korkmaz and H. Ozcelik, Afr. J. Biotechnol., 10 (47), 9533 (2011).
E Hanlidou, R. Karousou, V. Kleftoyanni, and S. Kokkini, J. Ethnopharmacol., 91, 281 (2004).
L. N. Ashurova, Kh. M. Bobakulov, N. Sh. Ramazonov, S. A. Sasmakov, O. N. Ashirov, Sh. S. Azimova, and N. D. Abdullaev, Chem. Nat. Compd., 57, 970 (2021).
T. Kubota, H. Kitatani, and H. Hinoh, Tetrahedron Lett., 10, 771 (1969).
S. Y. Woo, N. N. Win, W. M. Noe Oo, H. Ngwe, T. Ito, I. Abe, and H. Morita, J. Biosci. Bioeng., 128, 445 (2019).
Clinical and Laboratory Standards Institute (CLSI), Performance Standards for Antimicrobial Disk Susceptibility Tests. CLSI document M02, 13th Ed., PA, USA, 2018.
S. A. Sasmakov, Zh. M. Putieva, Sh. S. Azimova, and U. Lindequist, Asian J. Tradit. Med., 7 (2), 73 (2012).
Acknowledgment
The work was supported by the Budgetary Program of Basic Scientific Research, AS, RUz.
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2023, pp. 274–276.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Ashurova, L.N., Khurramov, A.R., Bobakulov, K. et al. Structure of a New Saponin from Saponaria officinalis growing in Uzbekistan. Chem Nat Compd 59, 323–326 (2023). https://doi.org/10.1007/s10600-023-03985-x
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10600-023-03985-x