One new tetralone derivative, designated as nigrospolone (1), was isolated from the n-BuOH-soluble fraction of the 95% EtOH extract of rice fermented with the endophytic fungus Nigrospora sp., derived from the medicinal plant Sacciolepis indica (L.) Chase. The structure was established on the basis of spectral analysis, especially according to the data obtained by two-dimensional nuclear magnetic resonance spectroscopy, high-resolution mass spectra experiments (HR-ESI-MS), and comparison of the spectroscopic data with those reported for structurally related compounds.
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References
G. A. Strobel and D. M. Long, ASM News, 64, 263 (1998).
G. A. Strobel, Crit. Rev. Biotechnol., 22, 315 (2002).
G. Strobel, B. Daisy, U. Castillo, and J. Harper, J. Nat. Prod., 67, 257 (2004).
L. P. Bush, H. H. Wilkinson, and C. L. Schardl, Plant Physiol., 114, 1 (1997).
R. X. Tan and W. X. Zou, Nat. Prod. Rep., 18, 448 (2001).
F. B. Sean, M. B. Shana, and C. Jon, J. Am. Chem. Soc., 123, 9900 (2001).
C. Lu and Y. Shen, J. Antibiot., 56, 415 (2003).
R. X. Tan and W. X. Zou, Nat. Prod. Rep., 18, 448 (2001).
H. M. Hsieh and Y. M. Ju, Mycol., 97, 844 (2005).
Y. M. Ju and J. D. Rogers, Mycotaxon, 73, 371 (1999).
M. J. Cheng, M. D. Wu, S. Y. Hsieh, M. T. Hsieh, I. S. Chen, and G. F. Yuan, Helv. Chim. Acta, 94, 1108 (2011).
N. W. Fan, H. S. Chang, M. J. Cheng, S. Y. Hsieh, T. W. Liu, G. F. Yuan, and I. S. Chen, Helv. Chem. Acta, 97, 1689 (2014).
C. C. Hsu, C. S. Kuoh, and H. Y. Liu, Gramineae (Poaceae), in: T. C. Huang, D. E. Boufford, C. F. Hsieh, C. S. Kuoh, H. Ohashi, and H. J. Su, (eds.), Flora of Taiwan, Vol. 5, 2nd Ed. Editorial Committee, Department of Botany, National Taiwan University, Taipei, Taiwan, 2000, p. 509.
Z. Y. Wu, Compendium of New China (Xinhua) Herbal, Vol. 3, Shanghai Science and Technology Publisher, Shanghai, 1991.
S. K. Talapatra, B. Karmacharya, S. C. De, and B. Talapatra, Phytochemistry, 27, 3929 (1988).
A. Fournet, A. A. Barrios, V. Munoz, R. Hocquemiller, F. Roblot, and A. Cave, Planta Med., 60, 8 (1994).
Acknowledgment
This work was kindly supported by the Food Industry Research and Development Institute (FIRDI) and supported by the Ministry of Science and Technology, R.O.C. (MOST-108-2320-B-080-002-, MOST-109-2622-E-080-001-, and MOST-110-2320-B-080-001-). The authors also thank Senior Technician Mrs. Chyi Jia Wang of the Center for Resources, Research and Development (CRRD) of Kaohsiung Medical University for measuring the 2D NMR data.
In addition, Ming-Der Wu and Ming-Jen Cheng contributed equally to this work.
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Published in Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2023 pp. 224–226
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Wu, MD., Cheng, MJ., Hsieh, SY. et al. Secondary Metabolites from the Endophytic Fungus Nigrospora sp., Derived from the Medicinal Plant Sacciolepis indica. Chem Nat Compd 59, 262–264 (2023). https://doi.org/10.1007/s10600-023-03971-3
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DOI: https://doi.org/10.1007/s10600-023-03971-3