Investigation of the ethyl acetate-soluble layer from the liquid fermentation of Phialophora lagerbergii, an endophytic fungus isolated from the Taiwanese endemic medicinal plant of Ardisia cornudentata var. cornudentata, led to the isolation of a new sesquiterpenoid, phialolagerol (1). The structure of the isolate was established by spectroscopic methods, including UV, IR, HR-ESI-MS, and extensive 1D and 2D NMR techniques, as well as by comparison with literature reports.
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Acknowledgment
This work was kindly supported by the Food Industry Research and Development Institute (FIRDI) and supported by Ministry of Science and Technology, R.O.C. (MOST-108-2320-B-080-002- & 110-2320-B-080 -001-).
All authors would like to thank Prof. Thanda Aung (Department of Chemistry Meiktila University, Mandalay Region, Myanmar) for her enthusiastic provision of many research documents to our team. We would like to express our deepest gratitude. The authors also thank Senior Technician Mrs. Chyi Jia Wang of Center for Resources, Research and Development (CRRD) of Kaohsiung Medical University for measuring the 2D NMR data.
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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2021, pp. 886–887.
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Cheng, MJ., Wu, MD., Chen, CY. et al. Metabolite from the Fungus of Phialophora lagerbergii. Chem Nat Compd 57, 1032–1034 (2021). https://doi.org/10.1007/s10600-021-03543-3
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DOI: https://doi.org/10.1007/s10600-021-03543-3