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Secondary Metabolite from the Fungal Strain Monascus pilosus

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Chemistry of Natural Compounds Aims and scope

A new benzopyran derivative, (–)-rel-5,7-dihydroxy-2-(4-methoxypentyl)-4,6-dimethylisochroman-8-one (1), was isolated from the red yeast rice of Monascus pilosus. The structure was determined by analyses of mass spectrometry and 1D and 2D NMR data. The relative configuration of the isolated compound was assigned on the basis of 2D NOESY experiments.

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Acknowledgment

This investigation was supported by a grant from the Ministry of Economic Affairs of Republic of China.

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Authors and Affiliations

  1. Bioresource Collection and Research Center (BCRC), Food Industry Research and Development Institute (FIRDI), 300, Hsinchu, Taiwan

    Ming-Jen Cheng, Ming-Der Wu, Hing-Yuen Chan & Gwo-Fang Yuan

  2. Natural Chemical Ind. Co. Ltd., 500, Changhua, Taiwan

    Yen-Chen Cheng

  3. Faculty of Pharmacy, School of Pharmaceutical Sciences, National Yang-Ming University, 112, Taipei, Taiwan

    Jih-Jung Chen

  4. Department of Medical Research, China Medical University Hospital, 404, Taichung, Taiwan

    Jih-Jung Chen & Yueh-Hsiung Kuo

  5. School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, 807, Kaohsiung, Taiwan

    Hsun-Shuo Chang

  6. Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, 40402, Taichung City, Taiwan

    Yueh-Hsiung Kuo

Authors
  1. Ming-Jen Cheng
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  2. Ming-Der Wu
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  3. Yen-Chen Cheng
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  4. Jih-Jung Chen
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  5. Hing-Yuen Chan
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  6. Hsun-Shuo Chang
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  7. Yueh-Hsiung Kuo
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  8. Gwo-Fang Yuan
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Corresponding authors

Correspondence to Ming-Jen Cheng or Jih-Jung Chen.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2017, pp. 743–745.

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Cheng, MJ., Wu, MD., Cheng, YC. et al. Secondary Metabolite from the Fungal Strain Monascus pilosus . Chem Nat Compd 53, 874–876 (2017). https://doi.org/10.1007/s10600-017-2144-7

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  • DOI: https://doi.org/10.1007/s10600-017-2144-7

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