A new bergenin derivative, 4-O-p-hydroxybenzoylbergenin (1), was isolated from the whole plants of Ardisia maclurei Merr., along with three known compounds wogonin (2), wogonoside (3), and α-spinasterol (4). The structure of 1 was elucidated using spectroscopic methods, mainly 2D NMR techniques. Compound 1 inhibited A549 cells with an IC50 value 20 μmol/mL.
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Acknowledgment
The research was supported by a grant from the Natural Science Foundation of Guangxi Province (2012GXNSFAA053020) and the Guangxi Key Laboratory of Chemistry and Engineering of Forest Products.
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Published in Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2016, pp. 197–199.
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Gu, Y., Li, P., Lei, F. et al. A New Bergenin Derivative from Ardisia maclurei . Chem Nat Compd 52, 224–226 (2016). https://doi.org/10.1007/s10600-016-1600-0
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DOI: https://doi.org/10.1007/s10600-016-1600-0