Amides of ∆ 8,13 -bicyclohomofarnesoic acid containing 1,2,4-triazole and carbazole rings were synthesized in eight steps from commercially available norambreinolide. The compounds were prepared by reacting the acid chloride with the heterocyclic amines 3-amino-1,2,4-triazole and N-aminocarbazole. Their structures were elucidated by spectral methods and x-ray crystal structure analyses.
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Translated from Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2015, pp. 589–593.
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Kuchkova, K.I., Arycu, A.N., Sekara, E.S. et al. Synthesis and Structure of Homodrimane Sesquiterpenoids Containing 1,2,4-Triazole and Carbazole Rings. Chem Nat Compd 51, 684–688 (2015). https://doi.org/10.1007/s10600-015-1384-7
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DOI: https://doi.org/10.1007/s10600-015-1384-7