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Predictors of Functioning and Recovery Among Men and Women Veterans with Schizophrenia

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Abstract

Gender differences may play a role in functional outcomes for individuals with schizophrenia. To better understand differences, an exploratory secondary analysis was conducted using data from a large, multi-site study of individuals with schizophrenia in treatment at Veterans Affairs medical centers. Participants completed surveys at baseline (n = 801; 734 men, 67 women) to assess demographics, symptoms, social supports, and recovery; and one year (n = 662; 604 men, 58 women) to assess quality of life and functioning. Hierarchical linear regressions examined interactions of baseline factors with functioning and quality of life. Women and men did not differ significantly in baseline social support, psychiatric symptoms, or recovery. Female gender predicted higher occupational functioning, while social functioning in men was inversely related to baseline symptom severity. Being married predicted higher quality of life for women, but not men. These findings may inform gender tailoring of services for schizophrenia.

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Funding

This work was supported by the Department of Veterans Affairs, Veterans Health Administration, Health Services Research and Development Service Quality Enhancement Research Initiative (QUERI; Grant No. MNT 03-213), and VA Desert Pacific Mental Illness Research, Education and Clinical Center (MIRECC). NG acknowledges support from a K12 (K12HS26407) career development award from the Agency for Healthcare Research and Quality and the Patient-Centered Outcomes Research Institute. AH is supported by a VA HSR&D Research Career Scientist Award (RCS 21-135).

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Correspondence to Nichole Goodsmith.

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The authors have no conflicts of interest to declare.

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This study was approved by Institutional Review Boards of all participating study sites.

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Informed consent was obtained from all individual participants included in the study.

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Disclaimer The views expressed in this article are those of the authors and do not necessarily reflect the position or policy of the United States Department of Veterans Affairs, the United States Government, or affiliated institutions, or of the American Psychiatric Association, its officers, trustees, or members.

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Goodsmith, N., Cohen, A.N., Pedersen, E.R. et al. Predictors of Functioning and Recovery Among Men and Women Veterans with Schizophrenia. Community Ment Health J 59, 110–121 (2023). https://doi.org/10.1007/s10597-022-00979-x

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  • DOI: https://doi.org/10.1007/s10597-022-00979-x

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