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The [3+2] cycloaddition reaction as an attractive way for the preparation of nicotine analogs (microreview)

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Chemistry of Heterocyclic Compounds Aims and scope

In this microreview, the application of [3+2] cycloaddition reactions in the synthesis of nicotine analogs is critically reviewed and analyzed on the basis of available literature data. It was found that [3+2] cycloaddition with the participation of differently functionalized azomethine ylides is particularly well represented. This enables the synthesis of nicotine analogs not available by other routes.

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Authors and Affiliations

  1. Department of Organic Chemistry and Technology, Cracow University of Technology, 24 Warszawska St, 31-155, Cracow, Poland

    Agnieszka Łapczuk

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  1. Agnieszka Łapczuk
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Correspondence to Agnieszka Łapczuk.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2023, 59(3), 109–111

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Łapczuk, A. The [3+2] cycloaddition reaction as an attractive way for the preparation of nicotine analogs (microreview). Chem Heterocycl Comp 59, 109–111 (2023). https://doi.org/10.1007/s10593-023-03171-5

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