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Multicomponent and domino reactions of 3-aroylacrylic acids in the synthesis of heterocycles

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Chemistry of Heterocyclic Compounds Aims and scope

This review generalizes the data available on heterocyclizations of 3-aroylacrylic acids and their esters, published over the previous 15 years. Multicomponent, cascade, and domino reactions, as well as cycloaddition and electrocyclization reactions involving 3-aroylacrylic acids and their esters have been used to obtain five- and six-membered aromatic and non-aromatic (including chiral) oxygen- or nitrogen-containing monocyclic heterocycles, spiro compounds, as well as condensed bi- and tricyclic systems.

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This work received financial support from the Russian Foundation for Basic Research (grant No. 14-03-01033) and the Ministry of Education and Science (State contract, project No. 4.1626.2014/K).

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Authors and Affiliations

  1. Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira St., Yekaterinburg, 620002, Russia

    Tetyana V. Beryozkina & Vasiliy A. Bakulev

  2. V. N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkiv, 61077, Ukraine

    Nadezhda N. Kolos

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  1. Tetyana V. Beryozkina
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  2. Nadezhda N. Kolos
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  3. Vasiliy A. Bakulev
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Correspondence to Tetyana V. Beryozkina.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2016, 52(9), 651–657

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Beryozkina, T.V., Kolos, N.N. & Bakulev, V.A. Multicomponent and domino reactions of 3-aroylacrylic acids in the synthesis of heterocycles. Chem Heterocycl Comp 52, 651–657 (2016). https://doi.org/10.1007/s10593-016-1945-0

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