Novel 3-acetyl-2-methyl-polyfluoro-4Н-chromen-4-ones were obtained via one-pot acylation of acetylacetone with polyfluorobenzoyl chlorides. These chromones were shown to form N-substituted 3-amino-1-[2-hydroxy(polyfluoro)phenyl]but-2-en-1-ones in reaction with aliphatic primary amines, esters of amino acids, and aqueous ammonia via opening of the pyrone ring and deacylation.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2015, 51(11/12), 961–968
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Shcherbakov, K.V., Bazhin, D.N., Burgart, Y.V. et al. Novel 3-acetyl-2-methyl-polyfluorochromones in reactions with amines and esters of amino acids. Chem Heterocycl Comp 51, 961–968 (2015). https://doi.org/10.1007/s10593-016-1805-y
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DOI: https://doi.org/10.1007/s10593-016-1805-y