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Nano and Sub-nano Gold–Cobalt Particles as Effective Catalysts in the Synthesis of Propargylamines via AHA Coupling

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Abstract

Titania supported Au–Co catalysts with nano- and sub-nanoparticles, were prepared with 1% Au and different contents of cobalt by one pot deposition precipitation with urea. Monometallic gold and cobalt catalysts were also prepared by the same method for a comparative purpose. The characterization of bimetallic catalyst evidenced the presence of sub-nanoparticles where 50% of cobalt and 40% of gold particles are smaller than 1 nm and the formation Au–Co particles. The results show a positive effect of cobalt on gold particles size and the catalytic activity. The effectiveness of these catalysts in the synthesis of several propargylamines via amine, CH2Cl2 and alkyne coupling (AHA coupling) was demonstrated. Different propargylamines were synthesized with very good yields (71%–88%). A comparative study of monometallic gold, monometallic cobalt and bimetallic gold–cobalt catalysts was investigated. The most efficient catalyst was reused for up to six reaction cycles without significant activity loss.

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Acknowledgements

This work was funding by the Algerian DGRSDT-MESRS, and the University of Tlemcen. The authors thank the company Thermo Fisher Scientific (Europe NanoPort-Eindhoven-Netherlands) and the company Sinal Algeria for their help in carrying out electron microscopy characterizations.

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Authors and Affiliations

  1. Laboratory of Catalysis and Synthesis in Organic Chemistry, University of Tlemcen, BP 119, Tlemcen, Algeria

    Meriem Bensaad, Amina Berrichi, Redouane Bachir & Sumeya Bedrane

  2. Sciences Institut, University Center Belhadj Bouchaib, BP 284, 46000, Ain Témouchent, Algeria

    Amina Berrichi

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  1. Meriem Bensaad
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Correspondence to Amina Berrichi.

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Bensaad, M., Berrichi, A., Bachir, R. et al. Nano and Sub-nano Gold–Cobalt Particles as Effective Catalysts in the Synthesis of Propargylamines via AHA Coupling. Catal Lett 151, 1068–1079 (2021). https://doi.org/10.1007/s10562-020-03382-x

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