Abstract
The 2022 AHA/ACC Guidelines for the Diagnosis and Management of Aortic Disease introduced important updates for managing thoracic aorta aortic disease (TAD). In particular, the Guidelines underscore multimodality imaging's role in diagnosis, risk assessment, and monitoring of patients with TAD. This commentary aims to distill key imaging aspects from the Guidelines to provide a concise reference for the cardiovascular imaging community. Primary areas of focus include: (1) The importance of imagers in the multidisciplinary TAD care team, (2) Appropriate imaging techniques along with their strengths and weaknesses, (3) Aortic measurement methods and how aortic size and growth should contribute to TAD risk assessment, (4) Imaging evaluation of acute aortic syndrome. We have also highlighted several areas of ongoing uncertainty and confusion, specifically related to aortic measurement techniques and descriptive terminology. Finally, a perspective on the future of TAD imaging is discussed with a focus on advanced imaging tools and techniques as well as the potential role of artificial intelligence.
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References
Isselbacher EM, Preventza O, Black JH, Augoustides JG, Beck AW, Bolen MA, Braverman AC, Bray BE, Brown-Zimmerman MM, Chen EP, Collins TJ, DeAnda A, Fanola CL, Girardi LN, Hicks CW, Hui DS, Jones WS, Kalahasti V, Kim KM, Milewicz DM, Oderich GS, Ogbechie L, Promes SB, Ross EG, Schermerhorn ML, Times SS, Tseng EE, Wang GJ, Woo YJ (2022) 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. Circulation 146(24):e334–e482. https://doi.org/10.1161/CIR.0000000000001106
Gunn AJ, Kalva SP, Majdalany BS, Craft J, Eldrup-Jorgensen J, Ferencik M, Ganguli S, Kendi AT, Khaja MS, Obara P, Russell RR, Sutphin PD, Vijay K, Wang DS, Dill KE (2021) ACR Appropriateness Criteria® Nontraumatic Aortic Disease. J Am College Radiol JACR 15(5):106–118
Goldstein SA, Evangelista A, Abbara S, Arai A, Asch FM, Badano LP, Bolen MA, Connolly HM, Cuéllar-Calàbria H, Czerny M (2015) Multimodality imaging of diseases of the thoracic aorta in adults: from the American Society of Echocardiography and the European Association of Cardiovascular Imaging: endorsed by the Society of Cardiovascular Computed Tomography and Society for Cardiovascular Magnetic Resonance. J Am Soc Echocardiogr 28(2):119–182
Elefteriades JA, Mukherjee SK, Mojibian H (2020) Discrepancies in measurement of the thoracic aorta: JACC review topic of the week. J Am Coll Cardiol 76(2):201–217
Allen BD, Bergmann LL (2021) Current Concepts in Acute Aortic Syndrome. Adv Clin Radiol 3:139–151. https://doi.org/10.1016/j.yacr.2021.04.012
Chin AS, Willemink MJ, Kino A, Hinostroza V, Sailer AM, Fischbein MP, Mitchell RS, Berry GJ, Miller DC, Fleischmann D (2018) Acute limited intimal tears of the thoracic aorta. J Am Coll Cardiol 71(24):2773–2785
Zilber ZA, Boddu A, Malaisrie SC, Hoel AW, Mehta CK, Vassallo P, Burris NS, Roldán-Alzate A, Collins JD, François CJ (2021) Noninvasive morphologic and hemodynamic evaluation of type B aortic dissection: state of the art and future perspectives. Radiology: Cardiothoracic Imaging. 3: 3 200456
Grist TM, Rubin GD. Imaging of Acute Aortic Syndromes. In: Hodler J, Kubik-Huch RA, von Schulthess GK, editors. Diseases of the Chest, Breast, Heart and Vessels 2019–2022: Diagnostic and Interventional Imaging. Cham (CH): Springer
Plonek T, Berezowski M, Bochenek M, Filip G, Rylski B, Golesworthy T, Jasinski M (2019) A comparison of aortic root measurements by echocardiography and computed tomography. J Thorac Cardiovasc Surg 157(2):479–486
Asch FM, Yuriditsky E, Prakash SK, Roman MJ, Weinsaft JW, Weissman G, Weigold WG, Morris SA, Ravekes WJ, Holmes KW (2016). The need for standardized methods for measuring the aorta: multimodality core lab experience from the GenTAC registry. JACC: Cardiovascular Imaging 9: 3 219–26
Rodriguez-Palomares JF, Teixido-Tura G, Galuppo V, Cuellar H, Laynez A, Gutierrez L, González-Alujas MT, Garcia-Dorado D, Evangelista A (2016) Multimodality assessment of ascending aortic diameters: comparison of different measurement methods. J Am Soc Echocardiogr 29(9):819–826
Roos JE, JrK W, Weishaupt D, Lachat M, Marincek B, Hilfiker PR (2002) Thoracic aorta: motion artifact reduction with retrospective and prospective electrocardiography-assisted multi–detector row CT. Radiology 222(1):271–277
de Heer LM, Budde RP, Mali WP, De Vos AM, Van Herwerden LA, Kluin J (2011) Aortic root dimension changes during systole and diastole: evaluation with ECG-gated multidetector row computed tomography. Int J Cardiovasc Imaging. https://doi.org/10.1007/s10554-011-9838-x
Frazao C, Tavoosi A, Wintersperger BJ, Nguyen ET, Wald RM, Ouzounian M, Hanneman K (2020) Multimodality assessment of thoracic aortic dimensions: comparison of computed tomography angiography, magnetic resonance imaging, and echocardiography measurements. J Thorac Imaging 35(6):399–406
Hanneman K, Chan FP, Mitchell RS, Miller DC, Fleischmann D (2016) Pre- and Postoperative Imaging of the Aortic Root. Radiographics. https://doi.org/10.1148/rg.2016150053
Paruchuri V, Salhab KF, Kuzmik G, Gubernikoff G, Fang H, Rizzo JA, Ziganshin BA, Elefteriades JA (2015) Aortic size distribution in the general population: explaining the size paradox in aortic dissection. Cardiology 131(4):265–272
Svensson LG, Khitin L (2002) Aortic cross-sectional area/height ratio timing of aortic surgery in asymptomatic patients with Marfan syndrome. J Thorac Cardiovasc Surg 123(2):360–361
Zafar MA, Li Y, Rizzo JA, Charilaou P, Saeyeldin A, Velasquez CA, Mansour AM, Mahmood SUB, Ma W-G, Brownstein AJ (2018) Height alone, rather than body surface area, suffices for risk estimation in ascending aortic aneurysm. J Thorac Cardiovasc Surg 155(5):1938–1950
Davies RR, Gallo A, Coady MA, Tellides G, Botta DM, Burke B, Coe MP, Kopf GS, Elefteriades JA (2006) Novel measurement of relative aortic size predicts rupture of thoracic aortic aneurysms. Ann Thorac Surg 81(1):169–177
Masri A, Kalahasti V, Svensson LG, Roselli EE, Johnston D, Hammer D, Schoenhagen P, Griffin BP, Desai MY (2016) Aortic Cross-Sectional Area/Height Ratio and Outcomes in Patients With a Trileaflet Aortic Valve and a Dilated Aorta. Circulation 134(22):1724–1737. https://doi.org/10.1161/CIRCULATIONAHA.116.022995
den Hartog AW, Franken R, de Witte P, Radonic T, Marquering HA, van der Steen WE, Timmermans J, Scholte AJ, van den Berg MP, Zwinderman AH (2013) Aortic disease in patients with Marfan syndrome: aortic volume assessment for surveillance. Radiology 269(2):370–377
Lombardi JV, Hughes GC, Appoo JJ, Bavaria JE, Beck AW, Cambria RP, Charlton-Ouw K, Eslami MH, Kim KM, Leshnower BG, Maldonado T, Reece TB, Wang GJ (2020) Society for Vascular Surgery (SVS) and Society of Thoracic Surgeons (STS) reporting standards for type B aortic dissections. J Vasc Surg 71(3):723–747. https://doi.org/10.1016/j.jvs.2019.11.013
Rodríguez-Palomares JF, Dux-Santoy L, Guala A, Kale R, Maldonado G, Teixidó-Turà G, Galian L, Huguet M, Valente F, Gutiérrez L (2018) Aortic flow patterns and wall shear stress maps by 4D-flow cardiovascular magnetic resonance in the assessment of aortic dilatation in bicuspid aortic valve disease. J Cardiovasc Magn Reson 20(1):1–15
Hope MD, Hope TA, Meadows AK, Ordovas KG, Urbania TH, Alley MT, Higgins CB (2010) Bicuspid aortic valve: four-dimensional MR evaluation of ascending aortic systolic flow patterns. Radiology 255(1):53–61
Guzzardi DG, Barker AJ, van Ooij P, Malaisrie SC, Puthumana JJ, Belke DD, Mewhort HE, Svystonyuk DA, Kang S, Verma S, Collins J, Carr J, Bonow RO, Markl M, Thomas JD, McCarthy PM, Fedak PW (2015) Valve-Related Hemodynamics Mediate Human Bicuspid Aortopathy: Insights From Wall Shear Stress Mapping. J Am Coll Cardiol. https://doi.org/10.1016/j.jacc.2015.06.1310
Soulat G, Scott MB, Allen BD, Avery R, Bonow RO, Malaisrie SC, McCarthy P, Fedak PW, Barker AJ, Markl M (2022) Association of regional wall shear stress and progressive ascending aorta dilation in bicuspid aortic valve. Cardiovasc Imaging 15(1):33–42
Burris NS, Fleischmann D, Hope MD. Blood Flow Patterns of Risk in Aortic Dissection: Time to Go With the Flow? : American College of Cardiology Foundation Washington DC; 2022. p. 2428–30.
Zhu T, Mian O, Boodhwani M, Beauchesne L, Dennie C, Chan K, Wells GA, Rubens F, Coutinho T (2023) Combining Aortic Size with Arterial Hemodynamics Enhances Assessment of Future Thoracic Aortic Aneurysm Expansion. Can J Cardiol 39(1):40–48
Zhu Y, Chen R, Juan Y-H, Li H, Wang J, Yu Z, Liu H (2018) Clinical validation and assessment of aortic hemodynamics using computational fluid dynamics simulations from computed tomography angiography. Biomed Eng Online 17:1–12
Karmonik C, Müller-Eschner M, Partovi S, Geisbüsch P, Ganten M-K, Bismuth J, Davies MG, Böckler D, Loebe M, Lumsden AB (2013) Computational fluid dynamics investigation of chronic aortic dissection hemodynamics versus normal aorta. Vascular Endovasc Surg 47(8):625–631
Si-Mohamed SA, Sigovan M, Hsu JC, Tatard-Leitman V, Chalabreysse L, Naha PC, Garrivier T, Dessouky R, Carnaru M, Boussel L (2021) In vivo molecular K-edge imaging of atherosclerotic plaque using photon-counting CT. Radiology 300(1):98–107
Bian Z, Zhong J, Dominic J, Christensen GE, Hatt CR, Burris NS (2022) Validation of a robust method for quantification of three-dimensional growth of the thoracic aorta using deformable image registration. Med Phys 49(4):2514–2530
Rueckel J, Reidler P, Fink N, Sperl J, Geyer T, Fabritius M, Ricke J, Ingrisch M, Sabel B (2021) Artificial intelligence assistance improves reporting efficiency of thoracic aortic aneurysm CT follow-up. Eur J Radiol 134:109424
Sherk WM, Khaja MS, Williams DM (2018) Aortic Dissection. In: Keefe NA, Haskal ZJ, Park AW, Angle JF (eds) IR Playbook: A Comprehensive Introduction to Interventional Radiology. Springer International Publishing, Cham, pp 209–218
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Bradley D. Allen: American Heart Association (20CDA35310687), American Roentgen Ray Society.
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All authors contributed to manuscript conception. A.H., M.G., P.S.R., B.D.A. drafted and critically revised the manuscript. S.A. and K.H. critically revised the manuscript. All authors approved the final version of the manuscript.
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Aws Hamid has no relevant financial or non-financial interests to disclose. Monesha Gupta has no relevant financial or non-financial interests to disclose. Prabhakar Shantha Rajiah has no relevant financial or non-financial interests to disclose. Suhny Abbara, MD, FACR. MSCCT: Royalties, Elsevier. Kate Hanneman: Honoria Sanofi, Amicus, Medscape, MRI Online. Bradley D. Allen: Speaking fees, Circle Cardiovascular Imaging; Research Support, Guerbet; Co-Founder and Shareholder, Third Coast Dynamics, Inc.
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Hamid, A., Gupta, M., Rajiah, P.S. et al. The current and future role of imaging of thoracic aortic disease: a North American society for cardiovascular imaging commentary on the 2022 AHA/ACC guidelines for the diagnosis and management of aortic disease. Int J Cardiovasc Imaging 40, 5–14 (2024). https://doi.org/10.1007/s10554-023-02964-1
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DOI: https://doi.org/10.1007/s10554-023-02964-1