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Magnetic resonance evaluation of cardiac thrombi and masses by T1 and T2 mapping: an observational study

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Abstract

The purpose of this work was to evaluate CMR T1 and T2 mapping sequences in patients with intracardiac thrombi and masses in order to assess T1 and T2 relaxometry usefulness and to allow better etiological diagnosis. This observational study of patients scheduled for routine CMR was performed from September 2014 to August 2015. All patients referred to our department for a 1.5 T CMR were screened to participate. T1 mapping were acquired before and after Gadolinium injection; T2 mapping images were obtained before injection. 41 patients were included. 22 presented with cardiac thrombi and 19 with cardiac masses. The native T1 of thrombi was 1037 ± 152 ms (vs 1032 ± 39 ms for myocardium, p = 0.88; vs 1565 ± 88 ms for blood pool, p < 0.0001). T2 were 74 ± 13 ms (vs 51 ± 3 ms for myocardium, p < 0.0001; vs 170 ± 32 ms for blood pool, p < 0.0001). Recent thrombi had a native T1 shorter than old thrombi (911 ± 177 vs 1169 ± 107 ms, p = 0.01). The masses having a shorter T1 than the myocardium were lipomas (278 ± 29 ms), calcifications (621 ± 218 ms), and melanoma (736 ms). All other masses showed T1 values higher than myocardial T1, with T2 consistently >70 ms. T1 and T2 mapping CMR sequences can be useful and represent a new approach for the evaluation of cardiac thrombi and masses.

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Abbreviations

CMR:

Cardiac magnetic resonance

HASTE:

Half-Fourier acquisition single-shot turbo spin-echo

LGE:

Late gadolinium enhancement

MRI:

Magnetic resonance imaging

MOLLI:

Modified Look-Locker inversion-recovery

ROI:

Region of interest

SSFP:

Steady-state free precession

STIR:

Short Tau-inversion recovery

Tx mapping:

T1 and T2 mapping software

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Authors and Affiliations

  1. Department of Cardiology, Nouvel Hôpital Civil, University Hospital of Strasbourg, Strasbourg, France

    Thibault Caspar, Aubrietia Lawson, Patrick Ohlmann & Olivier Morel

  2. Department of Radiology, Nouvel Hôpital Civil, University Hospital of Strasbourg, Strasbourg, France

    Soraya El Ghannudi, Mickaël Ohana, Aïssam Labani, Catherine Roy, Afshin Gangi & Philippe Germain

  3. ICube Laboratory, University of Strasbourg, CNRS, Strasbourg, France

    Soraya El Ghannudi, Mickaël Ohana, Michel De Mathelin & Afshin Gangi

  4. Pôle d’activité medico-chirurgicale cardiovasculaire, Nouvel Hôpital Civil, 1 Place de l’Hôpital, 67091, Strasbourg Cedex, France

    Thibault Caspar

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  1. Thibault Caspar
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  2. Soraya El Ghannudi
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  9. Catherine Roy
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Correspondence to Thibault Caspar.

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Caspar, T., El Ghannudi, S., Ohana, M. et al. Magnetic resonance evaluation of cardiac thrombi and masses by T1 and T2 mapping: an observational study. Int J Cardiovasc Imaging 33, 551–559 (2017). https://doi.org/10.1007/s10554-016-1034-6

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  • DOI: https://doi.org/10.1007/s10554-016-1034-6

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