Skip to main content
Log in

CT evaluation prior to transapical aortic valve replacement: semi-automatic versus manual image segmentation

  • Original Paper
  • Published:
The International Journal of Cardiovascular Imaging Aims and scope Submit manuscript

Abstract

To compare the performance of semi-automatic versus manual segmentation for ECG-triggered cardiovascular computed tomography (CT) examinations prior to transcatheter aortic valve replacement (TAVR), with focus on the speed and precision of experienced versus inexperienced observers. The preoperative ECG-triggered CT data of 30 consecutive patients who were scheduled for TAVR were included. All datasets were separately evaluated by two radiologists with 1 and 5 years of experience (novice and expert, respectively) in cardiovascular CT using an evaluation software program with or without a semi-automatic TAVR workflow. The time expended for data loading and all segmentation steps required for the implantation planning were assessed. Inter-software as well as inter-observer reliability analysis was performed. The CT datasets were successfully evaluated, with mean duration between 520.4 ± 117.6 s and 693.2 ± 159.5 s. The three most time-consuming steps were the 3D volume rendering, the measurement of aorta diameter and the sizing of the aortic annulus. Using semi-automatic segmentation, a novice could evaluate CT data approximately 12.3 % faster than with manual segmentation, and an expert could evaluate CT data approximately 10.3 % faster [mean differences of 85.4 ± 83.8 s (p < 0.001) and 59.8 ± 101 s (p < 0.001), respectively]. The inter-software reliability for a novice was slightly lower than for an expert; however, the reliability for a novice and expert was excellent (ICC 0.92, 95 % CI 0.75–0.97/ICC 0.96, 95 % CI 0.91–0.98). Automatic aortic annulus detection failed in two patients (6.7 %). The study revealed excellent inter-software and inter-observer reliability, with a mean ICC of 0.95. TAVR evaluation can be accomplished significantly faster with semi-automatic rather than with manual segmentation, with comparable exactness, showing a benefit for experienced and inexperienced observers.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

Abbreviations

3D VRT:

3D volume-rendering technique

AS:

Aortic valve stenosis

cMPR:

Curved multiplanar reconstruction

CT:

Computed tomography

ECG:

Electrocardiogram

ED:

Effective diameter

ICC:

Intraclass correlation coefficient

TAVR:

Transcatheter aortic valve replacement

References

  1. Leon MB, Smith CR, Mack M et al (2010) Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med 363:1597–1607

    Article  CAS  PubMed  Google Scholar 

  2. Kodali SK, Williams MR, Smith CR et al (2012) Two-year outcomes after transcatheter or surgical aortic valve replacement. N Engl J Med 366:1686–1695

    Article  CAS  PubMed  Google Scholar 

  3. Holmes DR Jr, Mack MJ, Kaul S et al (2012) 2012 ACCF/AATS/SCAI/STS expert consensus document on transcatheter aortic valve replacement. J Am Coll Cardiol 59:1200–1254

    Article  PubMed  Google Scholar 

  4. Lehmkuhl L, Foldyna B, Haensig M et al (2013) Role of preprocedural computed tomography in transcatheter aortic valve implantation. RoFo 184(10):941–949

    Article  CAS  PubMed  Google Scholar 

  5. Wilson AB, Webb JG, Freeman M et al (2012) Computed tomography-based sizing recommendations for transcatheter aortic valve replacement with balloon-expandable valves: comparison with transesophageal echocardiography and rationale for implementation in a prospective trial. J Cardiovasc Comput Tomogr 6:406–414

    Article  Google Scholar 

  6. Jilaihawi H, Kashif M, Fontana G et al (2012) Cross-sectional computed tomographic assessment improves accuracy of aortic annular sizing for transcatheter aortic valve replacement and reduces the incidence of paravalvular aortic regurgitation. J Am Coll Cardiol 59:1275–1286

    Article  PubMed  Google Scholar 

  7. Lehmkuhl L, Foldyna B, Von Aspern K et al (2013) Inter-individual variance and cardiac cycle dependency of aortic root dimensions and shape as assessed by ECG-gated multi-slice computed tomography in patients with severe aortic stenosis prior to transcatheter aortic valve implantation: is it crucial for correct sizing? Int J Cardiovasc Imaging 29(3):693–703

    Article  PubMed Central  PubMed  Google Scholar 

  8. Kempfert J, Van Linden A, Lehmkuhl L et al (2012) Aortic annulus sizing: echocardiographic vs. computed tomography derived measurements in comparison with direct surgical sizing. Eur J Cardiothorac Surg. doi:10.1093/ejcts/ezs064

  9. Tzikas A, Schultz CJ, Piazza N et al (2011) Assessment of the aortic annulus by multislice computed tomography, contrast aortography, and trans-thoracic echocardiography in patients referred for transcatheter aortic valve implantation. Catheter Cardiovasc Interv 77:868–875

    Article  PubMed  Google Scholar 

  10. Binder RK, Webb JG, Willson AB, Urena M, Hansson NC, Norgaard BL et al (2013) The impact of integration of a multidetector computed tomography annulus area sizing algorithm on outcomes of transcatheter aortic valve replacement: a prospective, multicenter, controlled trial. J Am Coll Cardiol 62:431–438

    Article  PubMed  Google Scholar 

  11. Stabile E, Sorropago G, Cioppa A et al (2010) Acute left main obstructions following TAVI. EuroIntervention 6:100–105

    Article  PubMed  Google Scholar 

  12. Gurvitch R, Webb JG, Yuan R et al (2011) Aortic annulus diameter determination by multidetector computed tomography: reproducibility, applicability, and implications for transcatheter aortic valve implantation. J Am Coll Cardiol Cardiovasc Interv 4:1235–1245

    Article  Google Scholar 

  13. Achenbach S, Delgado V, Hausleiter J, Schoenhagen P, Min JK, Leipsic JA (2012) SCCT expert consensus document on computed tomography imaging before transcatheter aortic valve implantation (TAVI)/transcatheter aortic valve replacement (TAVR). J Cardiovasc Comput Tomogr 6:366–380

    Article  PubMed  Google Scholar 

  14. Achenbach S, Schuhbäck A, Min JK, Leipsic J (2013) Determination of the aortic annulus plane in CT imaging-a step-by-step approach. J Am Coll Cardiol Imaging 6:275–278

    Article  Google Scholar 

  15. Hutter A, Opitz A, Bleiziffer S et al (2010) Aortic annulus evaluation in transcatheter aortic valve implantation. Catheter Cardiovasc Interv 76:1009–1019

    Article  PubMed  Google Scholar 

  16. Schuhbaeck A, Achenbach S, Pflederer T et al (2013) Reproducibility of aortic annulus measurements by computed tomography. Eur Radiol. doi:10.1007/s00330-014-3199-5

    PubMed  Google Scholar 

  17. Lücke C, Foldyna B, Andres C et al (2014) Post-processing in cardiovascular computed tomography: performance of a client server solution versus a stand-alone solution. Fortschr Röntgenstr 186:1111–1121

    Article  Google Scholar 

  18. Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174

    Article  CAS  PubMed  Google Scholar 

  19. Bland JM, Altman DG (1999) Measuring agreement in method comparison studies. Stat Methods Med Res 8:135–160

    Article  CAS  PubMed  Google Scholar 

  20. Lou J, Obuchowski NA, Krishnaswamy A et al (2014) Manual, semiautomated, and fully automated measurement of the aortic annulus for planning of transcatheter aortic valve replacement (TAVR/TAVI): analysis of interchangeability. J Cardiovasc Comput Tomogr 9(1):42–49

  21. Van Linden A, Kemfert J, Blumenstein J et al (2014) Manual versus automatic detection of aortic annulus plane in a computed tomographyscan for transcatheter aortic valve implantation screening. Eur J Cardiothorac Surg 46(2):207–212

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

The authors of this manuscript declare a cooperation contract between the Department of Interventional and Diagnostic Radiology of the Heart Center in Leipzig and the Siemens Company (Siemens AG, Healthcare, Erlangen, Germany), which supported the study and provided the required equipment and software.

Conflict of interest

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Borek Foldyna.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Foldyna, B., Jungert, C., Luecke, C. et al. CT evaluation prior to transapical aortic valve replacement: semi-automatic versus manual image segmentation. Int J Cardiovasc Imaging 31, 1233–1242 (2015). https://doi.org/10.1007/s10554-015-0662-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10554-015-0662-6

Keywords

Navigation